Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arginine aspartate is sometimes used to support the muscular system, particularly for claims related to reducing muscle fatigue and improving exercise capacity. The rationale is that arginine is a precursor to nitric oxide, which can promote vasodilation and potentially enhance blood flow to muscles, while aspartate may play a role in the citric acid cycle and energy metabolism. Some studies, particularly from the 1980s and 1990s, have investigated its effects on exercise performance and muscle fatigue, with mixed results. A few small-scale clinical trials reported modest improvements in exercise endurance and reduction in subjective fatigue, but these effects were generally limited and not consistently replicated in larger, more rigorous studies. The European Food Safety Authority (EFSA) reviewed the evidence and concluded that there is insufficient data to substantiate claims that arginine aspartate improves muscle function or reduces fatigue in the general population. Thus, while there is a scientific basis for its use and some early supportive findings, the overall level of evidence is weak (rated 2/5), and it is not considered a well-established or strongly validated supplement for muscle support.

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Other body systems supported by Arginine aspartate

Arteries
Blood
Circulatory System
Heart
Muscles

Products containing Arginine aspartate

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