Evidence supporting the use of: Betaine Nitrate
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Betaine nitrate is a compound combining betaine (trimethylglycine) and nitrate. Betaine itself has been studied for its potential to enhance physical performance, particularly through its role as a methyl donor, which may affect muscle function and body composition. Nitrate, on the other hand, is well recognized for its role in increasing nitric oxide production, which can improve blood flow, oxygen delivery, and exercise performance.
Scientific evidence for betaine nitrate’s effect on muscle support is emerging but not yet robust. Some studies on betaine supplementation (not specifically betaine nitrate) suggest modest improvements in muscle strength, power, and body composition, especially in resistance-trained individuals. Nitrate supplementation (often in the form of beetroot juice or sodium nitrate) has stronger evidence for enhancing exercise performance, particularly in endurance activities, by improving muscle efficiency and reducing oxygen cost.
However, direct studies on betaine nitrate as a unique compound are limited. Most claims are extrapolated from the known effects of betaine and nitrate individually. There are a few small studies and anecdotal reports suggesting potential synergistic effects, but large-scale, high-quality research is lacking. Thus, while there is a scientific rationale and some supportive evidence, the overall rating is moderate until more direct studies on betaine nitrate itself are published.
Other ingredients that support Muscles
acetyl l-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-proline
l-taurine
l-threonine
l-valine
magnesium
malic acid
maltodextrin
maltose
methylsulfonylmethane (MSM)
milk
nicotinamide riboside
ornithine alpha-ketoglutarate
peppermint oil
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
water
watermelon
whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
squawvine
sodium salt
solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
guelder rose
polyphenols
trace minerals
wintergreen
camphor oil
menthol oil
wheat germ
wood betony
herbal blend (proprietary)
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
arnica
17 alpha methyl 17 beta hydroxy 5 alpha androst 2 ene
17a-di methyl-bol
11-Ketotestosterone
2, 17a-dimethyl-17b-hydroxy-5a-androstan-1-ene-3-one
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
Arginine Alpha Ketoglutarate
Animal Tissue
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Avocado
Anserina
Alpha-ketoisocaproic acid
Acetylcholine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine alpha-ketoisocaproate
Arginine silicate
Animal protein
Blue Cohosh
Biopeptide
Beta-hydroxybutyrate
Bicarbonate
Beef Protein
Black galingale
Beef
Beef liver
Bovine Protein
Black Gram
Black willow
Ba Ji Tian
Bee products
banana
BCAA
Chia seed
Casein
Cardarine
Chinese Mountain Ant
Carnosine
Citrate malate
Cyathula
Curcuminoid
Cramp Bark
Chuchuhuasi
Cyanotis Vaga
Coca
Coconut Water
Cetylated Fatty Acids
Creatine
Chicken
Curcuma
C-Phycocyanin
Cyanotis arachnoides
DL-Methionine
Deer Velvet
Date
D-Ribose
Dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
epicatechin
Epistane
Egg
Erythrina
Elk antler
Emu Oil
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Essential Oil Blend
Egg protein
fibroblast growth factor
glucose
Glycine
Isoleucine
Milk Protein
Phosphate Salt
Potash
Quinoa Protein
salt
Soy Protein