Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the body system: Muscles

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Coenzyme Q10 (CoQ10) has a scientific rationale for use in supporting the muscular system, primarily due to its role in mitochondrial energy production. CoQ10 is an essential component of the electron transport chain, facilitating ATP synthesis—the main energy source for muscle contraction. Several clinical studies have investigated its benefits in individuals with muscle-related conditions. For example, patients with statin-induced myopathy (muscle pain caused by cholesterol-lowering drugs) have shown modest improvements in symptoms with CoQ10 supplementation, though results are mixed and not universally conclusive. Additionally, CoQ10 deficiency has been linked to certain rare myopathies, and supplementation may help in these contexts. In athletes and healthy individuals, CoQ10 supplementation has been studied for potential improvements in exercise performance, muscle fatigue, and recovery. Some studies report slight enhancements in exercise capacity and reduced markers of muscle damage, but the effects are generally small. Overall, while CoQ10’s role in muscle energy metabolism is well-established biochemically, the clinical evidence for supplementation benefiting muscle strength or function in healthy individuals is moderate at best (hence, a rating of 3). It is more strongly supported for specific populations experiencing muscle dysfunction related to statin use or mitochondrial disorders, rather than for general muscle support.

More about coenzyme Q10 (CoQ10)
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Other ingredients that support Muscles

Acetyl L-carnitine
Acetylcholine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Algae
Algal protein
Alpha hydroxyisocaproic acid
alpha-ketoglutarate (AKG)
Alpha-ketoisocaproic acid
amino acids
AMP-activated protein kinase (AMPK)
animal protein
animal Tissue
Anserina
antler
arachidonic acid
arginine alpha ketoglutarate
Arginine alpha-ketoisocaproate
Arginine aspartate
arginine creatine
Arginine malate
Arginine nitrate
Arginine silicate
arnica
ashwagandha
astaxanthin
avocado
ba ji tian
banana
BCAA
bee products
beef
Beef liver
Beef Protein
beet
beta-alanine
beta-hydroxybutyrate
bicarbonate
Biopeptide
black galingale
black ginger
black gram
Black willow
blue cohosh
bovine
bovine liver
bovine protein
branched-chain amino acids
bromelain
brown rice protein
C-phycocyanin
caffeine
calcium
camphor oil
cardarine
Carnosine
casein
Cetylated Fatty Acids
cherry
chia seed
chickpea protein
Chinese mountain ant
chloride
chuchuhuasi
citrate malate
coca
Coconut Water
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
cramp bark
creatine
creatine monohydrate
Curcuma
Curcuminoid
Cyanotis arachnoides
Cyanotis vaga
Cyathula
d-alpha tocopherol
D-Ribose
date
deer velvet
devil's claw
dextrose
Dimethyl sulfoxide (DMSO)
Dipeptide
Dipsacus
DL-Methionine
dong quai root
ecdysteroids
ecdysterone
egg
Egg protein
electrolytes blend (proprietary)
elk antler
emu oil
epicatechin
epistane
Erythrina
essential oil blend
Ethyl-Alpha-Guanido-Methyl-Ethanoate
eucommia
Eurycoma Longifolia
fatty acids
fibroblast growth factor
fish
fish protein
forskohlii root
Ginsenosides
glucose
Glutamine
Glycerol
Glycine
Glycocyamine
GMS-ribose
guanidinoacetic acid
guanidinopropionic acid (GPA )
guelder rose
Haematococcus pluvialis
hairy arnica
herbal blend (proprietary)
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
Iporuru
iron
Isoleucine
isomaltulose
kale
ketosterones
L-alanine
L-alanyl-L-glutamine
L-arginine
l-carnitine
L-carnosine
L-citrulline
L-glutamine
L-glycine
l-isoleucine
L-leucine
L-ornithine
L-proline
L-taurine
L-threonine
L-valine
lactalbumin
Lavandin
Legume protein
Lentein
Lentil
leucine alpha-ketoglutarate
lipids
magnesium
malic acid
maral root
Marine protein
Marjoram
Maslinic acid
Menthol oil
Methylsulfonylmethane (MSM)
Methylxanthine
Milk
Milk Protein
Mineral ascorbate
Mineral blend
NADH
nicotinamide riboside
Ornithine
ornithine alpha-ketoglutarate
Pea
Peppermint
Peptides
Phosphatidic Acid
Phosphocreatine
phosphorus
phytocannabinoids
Phytoecdysteroid
Plankton
polyphenols
potash
potassium
Propionyl-L-Carnitine
protein
proteolytic enzymes
Puerain
pyruvate
Qin Jiao
quinoa
Quinoa Protein
Rhaponticum
rhizome
ribose
rue
Safed musli
Salmon Oil
salt
Shilajit
Sida cordifolia
siler root
solomon's seal
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
squawvine
suma
Taurine
Taxillus sutchuenensis
Terpenoids
Tongkat ali
trace minerals
Tribulus Terrestris
Trichopus zeylanicus
Turkesterone
turmeric
Tynanthus panurensis
ubiquinol
Urolithin A
Ursolic Acid
Vegetable Protein
Viburnum
vitamin B
vitamin C
vitamin D
vitamin D3
Watermelon
wheat germ
Whey protein
white willow
Wintergreen
Withanolides
Wood betony
β-nicotinamide mononucleotide (NMN)

Products containing coenzyme Q10 (CoQ10)

Pure Encapsulations Athletic Nutrients
Douglas Laboratories Citrus-Q10 ™
Douglas Laboratories Co-Enzyme Q10 Softgel
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics CoQ10
Integrative Therapeutics COQ10 100 mg Tropical
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Integrative Therapeutics COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations CoQ10 250 mg
Pure Encapsulations CoQ10 30 mg
Pure Encapsulations CoQ10 500 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 l-Carnitine Fumarate
Thorne CoQ10 Q-Best 100
Metagenics CoQ10 ST®-100 mg
Metagenics CoQ10 ST-100 mg
Metagenics CoQ10 ST-200 mg
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations Hair/Skin/Nails Ultra
Thorne Heart Health Complex Q-10 Plus
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Designs For Health Mito-NR™
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Pure Encapsulations NeuroMood Pure Pack
Metagenics NutraGems® CoQ10 300
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Thorne Omega-3 w/ CoQ10
Thorne Ovarian Care
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations PureGenomics® UltraMultivitamin
Designs For Health Q-Evail® 100
Designs For Health Q-Evail® 200
Pure Encapsulations Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations Renual
Pure Encapsulations RevitalAge™ Nerve
Pure Encapsulations RevitalAge™ Ultra
Designs For Health RYR Synergy™
Pure Encapsulations SR-CoQ10 with PQQ
Vitabase Super Fat Burner
Pure Encapsulations Ubiquinol-QH 100 mg
Pure Encapsulations Ubiquinol-QH 200 mg
Pure Encapsulations Ubiquinol VESIsorb®
Integrative Therapeutics UBQH 100 mg
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories Ultra Preventive One Daily
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations UltraDetox 10-Day Pure Pack
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Metagenics Wellness Essentials Brain Health Daily Packs