Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-citrulline is supported by scientific evidence as a supplement to support the muscles body system, particularly in the context of exercise performance and recovery. L-citrulline is a non-essential amino acid that plays a role in the urea cycle and is a precursor to L-arginine, which is a substrate for nitric oxide (NO) synthesis. Increased NO levels can lead to vasodilation, thereby improving blood flow to skeletal muscles during exercise. Several studies have shown that L-citrulline supplementation can enhance exercise performance by reducing fatigue and muscle soreness, and by increasing the production of ATP during high-intensity workouts. For example, randomized controlled trials have demonstrated that both acute and chronic supplementation with L-citrulline or citrulline malate can improve performance in resistance training and aerobic exercise, as well as decrease muscle soreness after exercise. However, the magnitude of these effects is generally moderate, and some studies have shown mixed results. Overall, the use of L-citrulline to support muscle function and exercise performance is scientifically plausible with moderate evidence, but more large-scale, long-term studies are needed for definitive conclusions.

More about L-citrulline
More about Muscles

Other ingredients that support Muscles

Other body systems supported by L-citrulline

Products containing L-citrulline

Douglas Laboratories Cysto Renew ®
Pure Encapsulations Nitric Oxide Support
Pure Encapsulations Nitric Oxide Ultra
Designs For Health NOx Synergy™