Evidence supporting the use of: Magnesium
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Magnesium is extensively studied and recognized for its role in muscle function. It is an essential mineral involved in over 300 enzymatic reactions in the body, many of which are critical for muscle contraction and relaxation. Magnesium helps regulate neuromuscular signals and muscle contractions by acting as a natural calcium blocker, helping muscles relax after contracting. Deficiency in magnesium is associated with symptoms like muscle cramps, spasms, and weakness. Several randomized controlled trials and meta-analyses have investigated magnesium supplementation for muscle cramps, particularly in older adults and pregnant women, with mixed but generally positive effects for those who are deficient. For example, a 2012 Cochrane review found limited evidence for benefit in the general population but suggested possible efficacy in specific groups.
Athletes may also use magnesium supplements to reduce the risk of exercise-induced muscle cramps or to support recovery, although direct performance enhancement is less conclusively demonstrated. The National Institutes of Health and other authoritative sources acknowledge magnesium’s key role in muscle health and recommend meeting daily requirements through diet or supplements if needed. In summary, the use of magnesium to support the muscle body system is scientifically justified, especially in cases of deficiency or increased demand.
Other ingredients that support Muscles
Acetyl L-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
L-alanine
L-alanyl-L-glutamine
L-arginine
l-carnitine
L-carnosine
L-citrulline
L-glutamine
L-glycine
L-leucine
L-ornithine
L-proline
L-taurine
L-threonine
L-valine
magnesium
malic acid
maltodextrin
maltose
Methylsulfonylmethane (MSM)
Milk
nicotinamide riboside
ornithine alpha-ketoglutarate
Peppermint
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
Tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
Water
Watermelon
Whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
squawvine
sodium salt
solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
guelder rose
polyphenols
trace minerals
Wintergreen
camphor oil
Menthol oil
wheat germ
Wood betony
herbal blend (proprietary)
Algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
arnica
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
arginine alpha ketoglutarate
animal Tissue
antler
arginine creatine
Arginine nitrate
arachidonic acid
Arginine malate
Arginine aspartate
avocado
Anserina
Alpha-ketoisocaproic acid
Acetylcholine
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine alpha-ketoisocaproate
Arginine silicate
animal protein
blue cohosh
Biopeptide
beta-hydroxybutyrate
bicarbonate
Beef Protein
black galingale
beef
Beef liver
bovine protein
black gram
Black willow
ba ji tian
bee products
banana
BCAA
chia seed
casein
cardarine
Chinese mountain ant
Carnosine
citrate malate
Cyathula
Curcuminoid
cramp bark
chuchuhuasi
Cyanotis vaga
coca
Coconut Water
Cetylated Fatty Acids
creatine
chicken
Curcuma
C-phycocyanin
Cyanotis arachnoides
DL-Methionine
deer velvet
date
D-Ribose
dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
epicatechin
epistane
egg
Erythrina
elk antler
Eurycoma Longifolia
emu oil
ecdysteroids
Ethyl-Alpha-Guanido-Methyl-Ethanoate
ecdysterone
essential oil blend
Egg protein
fish
fatty acids
fibroblast growth factor
guanidinoacetic acid
Ginsenosides
Glutamine
Growth factors
GMS-ribose
glucose
Glycocyamine
Glycerol
Glycine
guanidinopropionic acid (GPA )
hydroxymethylbutyrate
Haematococcus pluvialis
HMB hydroxymethylbutyrate
hairy arnica
isomaltulose
Iporuru
Isoleucine
icariin
ketosterones
Legume protein
Lentil
Lavandin
Lentein
leucine alpha-ketoglutarate
lactalbumin
lipids
Mineral blend
maral root
Maslinic acid
Mineral ascorbate
Marjoram
Marine protein
Milk Protein
Methylxanthine
NADH
Ornithine
Phosphocreatine
Puerain
Phytoecdysteroid
Plankton
Propionyl-L-Carnitine
proteolytic enzymes
Phosphate Salt
pyruvate
Phosphatidic Acid
Pea
potash
Peptides
Qin Jiao
Quinoa Protein
rue
Rhaponticum
ribose
Shellfish
Salmon Oil
Safed musli
salt
Soy Protein
Sida cordifolia
Shilajit
Terpenoids
Tripeptide
Taxillus sutchuenensis
Turkesterone
Trichopus zeylanicus
Taurine
Tynanthus panurensis
Tribulus Terrestris
Ursolic Acid
Vegetable Protein
Viburnum
Withanolides
Other body systems supported by magnesium
AcetylcholineAdrenal Glands
Arteries
Blood
Brain
Circulatory System
Cortisol
Digestive System
Dopamine
Dopamine
GABA
Glandular System
Heart
Heart
Hypothalamus
Immune System
Intestinal System
Large Intestines (Colon)
Male Reproductive System
Mitochondria
Muscles
Nerves
Ovaries
Parasympathetic Nervous System
Parathyroid Glands
Progesterone
Reproductive System
Senses
Serotonin
Skeletal System (Bones)
Skin
Small Intestines
Solar Plexus
Specific Hormones
Stomach
Structural System
Sympathetic Nervous System
Teeth
Testes
Testosterone
Thyroid Gland
Uterus
Veins
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Vitabase
Active Man's Formula
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Active Woman's Multi
Metagenics
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Adreset
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Adreset
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AdvaClear
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AdvaClear
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Advanced Nutrients Multivitamin
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Akkermansia Co.™ Healthy Weight with Glucose Control
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ArginCor®
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Ascorbplex ® 1000 Buffered
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Axis Endo™ Mango
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Ayur-Ashwagandha
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B12-Active
YH International
Barleygreen
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BioPure Protein® Powder
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Blisphora®
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Blood Pressure Support
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Bone Builder Active
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Bone Builder Plus
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Bone Builder Magnesium
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Bone Builder Vegetarian
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Caprylic Acid
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Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
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Clear Change 10-Day Detox Program with UltraClear RENEW Berry
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Clear Change 10-Day Detox Program with UltraClear RENEW Chai
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Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
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Clear Change 28-Day Detox Program with UltraClear Plus Berry
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Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
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Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
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Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Clear Change Daily Essentials
Integrative Therapeutics
Clinical Nutrients HP
Pure Encapsulations
CogniMag
Metagenics
Collagenics®
Designs For Health
Colon Rx™
Designs For Health
Complete Mineral Complex
Metagenics
Cortico-B5B6®
Integrative Therapeutics
Cortisol Manager
Douglas Laboratories
Cysto Renew ®
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Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Designs For Health
DFH Complete Multi™
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DFH Complete Multi™ with Copper
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DFH Complete Multi™ with Copper & Iron
Integrative Therapeutics
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Metagenics
Echinacea Synergy
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Electrolyte/Energy Formula
Designs For Health
Electrolyte Synergy™
Designs For Health
ElectroPure Hydration™
Metagenics
Endura® Lemonade
Pure Encapsulations
Energize Plus™ Pure Pack
Metagenics
EstroFactors®
Metagenics
Fem Prenatal®
Designs For Health
FemGuard+Balance™
Metagenics
Fenugreek Plus®
Metagenics
Fibroplex®
Designs For Health
GI Microb-X™
Designs For Health
GI Microb-X™
Metagenics
GI Sustain™ Powder
Pure Encapsulations
GlucoFunction
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GlucoFunction
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Glutagenics
Integrative Therapeutics
Glycemic Manager
Metagenics
Glycogenics
Douglas Laboratories
Hair, Skin and Nails Plus
Vitabase
Hair, Skin & Nails Formula
Vitabase
Healthy Sleep Support
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Heart Health Complex Q-10 Plus
Metagenics
HerSynergy®
Metagenics
HisSynergy™
Metagenics
ImmuCore
Metagenics
Immune Active
Metagenics
Immune Defense Pack
Metagenics
Insulin Guard
Integrative Therapeutics
K-PAX MitoNutrients
Metagenics
Ketogenic Shake Chocolate
Metagenics
Ketogenic Shake Vanilla
Klean Athlete
Klean Electrolytes ™
Klean Athlete
Klean Hydration™
Klean Athlete
Klean Hydration™
Klean Athlete
Klean Magnesium
Klean Athlete
Klean Multivitamin ™
Integrative Therapeutics
Krebs Magnesium/Potassium
Metagenics
L-Carnitine
Integrative Therapeutics
L-Theanine
Vitabase
Life's Essentials Plus
Metagenics
Lipo-Gen™
Metagenics
Lipo-Gen
Metagenics
Lipotain®
Integrative Therapeutics
Lipotropic Complex
Douglas Laboratories
Liquid Cal/Mag/D
Integrative Therapeutics
Liquid Calcium Magnesium Berry Flavored
Pure Encapsulations
Liquid Magnesium
Douglas Laboratories
Liquid Magnesium
Pure Encapsulations
Liquid Magnesium Glycinate
Douglas Laboratories
Liquid Multivitamin
Pure Encapsulations
LiquiNutrients
Metagenics
Mag Citrate™
Metagenics
Mag L-Threonate
Designs For Health
MagCitrate Powder
Pure Encapsulations
Magnesium
Thorne
Magnesium Bisglycinate NSF
Designs For Health
Magnesium Chelate
Designs For Health
Magnesium Glycinate Powder
Thorne
Magnesium CitraMate
Douglas Laboratories
Magnesium Citrate
Pure Encapsulations
Magnesium Citrate
Pure Encapsulations
Magnesium Citrate
Douglas Laboratories
Magnesium Citrate
Pure Encapsulations
Magnesium Citrate and Malate
Pure Encapsulations
Magnesium Citrate and Malate
Douglas Laboratories
Magnesium Glycinate
Pure Encapsulations
Magnesium Glycinate
Metagenics
Magnesium Glycinate
Pure Encapsulations
Magnesium Glycinate
Pure Encapsulations
Magnesium Glycinate
Metagenics
Magnesium Glycinate
Douglas Laboratories
Magnesium Glycinate
Designs For Health
Magnesium Glycinate Complex
Designs For Health
Magnesium Glycinate Complex
Designs For Health
Magnesium Glycinate Complex
Integrative Therapeutics
Magnesium Glycinate Plus
Designs For Health
Magnesium Malate
Designs For Health
Magnesium Malate
Integrative Therapeutics
Magnesium Malate
Douglas Laboratories
Magnesium Oxide
Douglas Laboratories
Magnesium Oxide
Douglas Laboratories
Magnesium/ Potassium Complex
Douglas Laboratories
Magnesium/ Potassium Complex
Pure Encapsulations
Magnesium Powder
Douglas Laboratories
Magnesium Taurate 400
Integrative Therapeutics
Magtein L-Threonate Plus
Douglas Laboratories
Malic Acid + Magnesium
Thorne
MediClear Plus
Thorne
Men's Multi 50+
Metagenics
Meta I 3 C®
Metagenics
Meta I 3 C
Metagenics
Meta Lipoate® 300 mg
Designs For Health
Metabolic Synergy™
Designs For Health
Metabolic Synergy™
Metagenics
MetaGlycemX™
Metagenics
MetaGlycemX
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MetaKids Nutrition Powder Chocolate
Metagenics
MetaKids Nutrition Powder Vanilla
Metagenics
MetaKids Probiotic
Metagenics
MetaKids Probiotic
Metagenics
MetaRelax®
Metagenics
MetaSleep®
Metagenics
MethylCare
Metagenics
Mg/K Aspartate™
Designs For Health
Migranol™
Pure Encapsulations
Mineral 650
Pure Encapsulations
Mineral 650 without Cu &Fe
Pure Encapsulations
Mitochondria-ATP
Metagenics
MitoVive
Integrative Therapeutics
Motility Activator
Thorne
Multi-Vitamin Elite NSF
Thorne
Multi-Vitamin Elite NSF
Metagenics
Multigenics®
Metagenics
Multigenics Chewable Orange
Metagenics
Multigenics Intensive Care
Metagenics
Multigenics Intensive Care without Iron
Metagenics
Multigenics without Iron
Integrative Therapeutics
Multiplex-1 No-Iron
Pure Encapsulations
Muscle Cramp/Tension Formula
Pure Encapsulations
Muscle Cramp/Tension Formula
Metagenics
MyoCalm
Metagenics
MyoCalm®
Metagenics
MyoCalm
Metagenics
MyoCalm Plus
Metagenics
MyoCalm Plus
Designs For Health
MyoSedate™
Designs For Health
NeuroCalm™
Designs For Health
NeuroMag™
Pure Encapsulations
NeuroMood Pure Pack
Metagenics
Niatain®
Designs For Health
NOx Synergy™
Pure Encapsulations
Nutrient 950®
Pure Encapsulations
Nutrient 950®
Pure Encapsulations
Nutrient 950®
Pure Encapsulations
Nutrient 950® A without Copper & Iron
Pure Encapsulations
Nutrient 950® with NAC
Pure Encapsulations
Nutrient 950® with Vitamin K
Pure Encapsulations
Nutrient 950® without Copper, Iron & Iodine
Pure Encapsulations
Nutrient 950® without Iron
Pure Encapsulations
Nutrient 950® without Iron
Integrative Therapeutics
Nutrivitamin No-Iron
Pure Encapsulations
OsteoBalance
Pure Encapsulations
OsteoBalance
Designs For Health
Osteoben®
Designs For Health
OsteoForce™
Designs For Health
OsteoForce™
Designs For Health
OsteoForce™ Supreme
Integrative Therapeutics
Osteoprime Forte
Integrative Therapeutics
Osteoprime Ultra
Metagenics
OsteoVantiv®
Metagenics
Ostera®
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health
PaleoMeal®
Designs For Health
PaleoMeal®
Metagenics
Perimine®
Integrative Therapeutics
Physicians Elemental Diet Dextrose Free
Integrative Therapeutics
Physician's Elemental Diet
Integrative Therapeutics
Physician's Elemental Diet
Integrative Therapeutics
Physicians Elemental Diet Kit
Metagenics
PhytoMulti™ Multivitamin
Metagenics
PhytoMulti With Iron
Metagenics
PhytoMulti Without Iron
Metagenics
PhytoMultivitamin
Designs For Health
Plant Protein Cleanse
Designs For Health
Plant Protein Cleanse Plus™ 570g
Metagenics
PlusOne® Daily Prenatal Packs
Pure Encapsulations
Polyphenol Nutrients
Pure Encapsulations
Polyphenol Nutrients
Pure Encapsulations
Potassium/Magnesium Aspartate
Pure Encapsulations
Potassium/Magnesium Aspartate
Pure Encapsulations
Potassium Magnesium Citrate
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Prenatal
Pure Encapsulations
PreNatal Nutrients
Pure Encapsulations
PreNatal Nutrients
Designs For Health
Prenatal Pro™
Designs For Health
PreTrain NRG™
Designs For Health
Primal Multi™
Integrative Therapeutics
Pro.Som
Integrative Therapeutics
ProThrivers Wellness Sleep
Pure Encapsulations
PureGenomics® Multivitamin
Pure Encapsulations
PureGenomics® UltraMultivitamin
Pure Encapsulations
PureLean® Fiber
Pure Encapsulations
PureLean® Protein
Pure Encapsulations
PurePals
Pure Encapsulations
PurePals with Iron
Pure Encapsulations
PureResponse™ Multivitamin
Metagenics
Quercetin 500
Douglas Laboratories
Quercetin-Bromelain Complex
Thorne
RecoveryPro NSF
Vitabase
Relaxation Support
Metagenics
Renagen™ DTX
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RevitalAge™ Nerve
Integrative Therapeutics
Riboflavin
Metagenics
Serenagen®
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Serenagen
Pure Encapsulations
SeroPlus
Metagenics
Silymarin 80™
Metagenics
SpectraZyme Gluten Digest
Metagenics
SpectraZyme Gluten Digest
Metagenics
SpectraZyme Betaine HCI + Pepsin
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SpectraZyme Metagest
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SulforaClear®
Vitabase
Super Stress Formula
Integrative Therapeutics
Testosterone Formula
Metagenics
Thyrosol
Metagenics
Tran-Q® Sleep
Metagenics
Trancor®
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Tri-Magnesium
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TriMag Supreme™
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TriMag Supreme™ Night Powder
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Ultra Glucose Control® Chocolate
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Ultra Glucose Control Chocolate
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Ultra Glucose Control Vanilla
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Ultra Glucose Control Vanilla
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Ultra Potent-C 1000
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Ultra Potent-C 500
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Ultra Potent-C Chewable
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Ultra Potent-C Powder
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Ultra Preventive
Douglas Laboratories
Ultra Preventive ® 2 Daily
Douglas Laboratories
Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories
Ultra Preventive ®-EZ Swallow
Douglas Laboratories
ULTRA PREVENTIVE® III W/COPPER
Douglas Laboratories
Ultra Preventive ® Kids Grape Flavor
Douglas Laboratories
Ultra Preventive ® Kids Orange Flavor
Douglas Laboratories
Ultra Preventive® X
Metagenics
Ultra Prostagen Concentrated
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Ultra Protein Green
Pure Encapsulations
Ultra Pure Pack
Metagenics
UltraClear Detox Powder
Metagenics
UltraClear Plus® Detox Powder
Metagenics
UltraClear Plus Detox Powder Berry
Metagenics
UltraClear Plus Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Vanilla
Metagenics
UltraClear RENEW Detox Powder Berry
Metagenics
UltraClear RENEW Detox Powder Chai
Metagenics
UltraClear RENEW Detox Powder Vanilla
Metagenics
UltraFlora Acute Care Probiotic
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UltraFlora Balance Probiotic
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UltraFlora Balance Probiotic
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UltraFlora BiomePro Probiotic
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UltraFlora Complete Women's Probiotic
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UltraFlora Control Probiotic
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UltraFlora IB Probiotic
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UltraFlora Immune Booster Probiotic
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UltraFlora Intensive Care Probiotic
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UltraFlora Restore Probiotic
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UltraFlora Triplebiotic
Metagenics
UltraFlora Women's Probiotic
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UltraGI Replenish® Chocolate
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UltraGI Replenish Chocolate
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UltraGI Replenish Vanilla
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UltraGI Replenish Vanilla
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UltraInflamX Plus 360°® Chocolate/Orange
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UltraInflamX Plus 360° Mango
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UltraInflamX Plus 360° Mango
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UltraInflamX Plus 360° Orange
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UltraInflamX Plus 360° Original Spice
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UltraInflamX Plus 360° Pineapple/Banana
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UltraInflamX Plus 360° Pineapple/Banana
Pure Encapsulations
UltraMag Magnesium
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UltraMeal Advanced Protein® Dutch Chocolate
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UltraMeal Advanced Protein French Vanilla
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UltraMeal Advanced Protein Plain
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UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics
UltraMeal Cardio 360° Pea/Rice Vanilla
Metagenics
UltraMeal® Daily Support Dutch Chocolate
Metagenics
UltraMeal Daily Support Mixed Berry
Metagenics
UltraMeal Rice Vanilla
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
Vascular Relax
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Vasotensin®
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Vitamin C Buffered Powder
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Wellness Essentials Men's Vitality Daily Packs
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Wellness Essentials Women's Daily Packs
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Wellness Essentials Women's Prime Daily Packs
Designs For Health
Whole Beauty Collagen™
Thorne
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Pure Encapsulations
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Zinc A.G.
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Zinc A.G.™