Evidence supporting the use of: Testosterone precursor (unspecified)
For the body system: Muscles

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Testosterone precursors, such as dehydroepiandrosterone (DHEA) and androstenedione, are compounds that the body can convert into testosterone. These substances have been marketed and used with the aim of supporting muscle growth and improving physical performance, based on the well-established role of testosterone in muscle protein synthesis and hypertrophy. There is some scientific rationale for their use, as higher testosterone levels are associated with increased muscle mass and strength. However, the actual effectiveness of testosterone precursors in significantly enhancing muscle growth in healthy individuals is limited.

Clinical studies on DHEA and androstenedione supplementation in both young and older adults have shown mixed results. While some research indicates a minor increase in serum testosterone levels, most well-designed studies do not demonstrate significant improvements in muscle mass, strength, or athletic performance compared to placebo. Furthermore, concerns exist regarding the safety of unsupervised use, including potential adverse effects such as hormonal imbalances and increased risk of cardiovascular or liver issues.

In summary, while the use of testosterone precursors to support the muscular system is grounded in scientific understanding of hormone physiology, robust evidence supporting their efficacy in muscle enhancement for healthy individuals is lacking or inconsistent. Thus, scientific support exists but is weak, and widespread recommendation is not currently backed by strong clinical data.

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amino acids
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Other body systems supported by Testosterone precursor (unspecified)

Male Reproductive System
Muscles
Reproductive System
Testes
Testosterone

Products containing Testosterone precursor (unspecified)

We currently have no products on Vitabase that contain this ingredient.