Relationship: Muscular Dystrophy and coenzyme Q10 (CoQ10)

Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Muscular Dystrophy

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) is used to support the treatment of Muscular Dystrophy based on limited scientific evidence. CoQ10 is a vital component of the mitochondrial electron transport chain and is essential for ATP (energy) production in muscle cells. In some types of muscular dystrophy, mitochondrial dysfunction and increased oxidative stress are believed to contribute to muscle cell damage and progression of the disease. Several small studies and case reports have investigated the potential benefits of CoQ10 supplementation in patients with muscular dystrophy, primarily Duchenne Muscular Dystrophy (DMD) and other myopathies.

Some of these studies have demonstrated modest improvements in muscle strength, physical performance, or biochemical markers when patients received CoQ10 supplements. For example, a few open-label and double-blind trials in children with DMD have noted slight increases in muscle strength or stabilization of function, though these effects were generally small and not always statistically significant. The evidence base is limited by small sample sizes, short study durations, and variability in CoQ10 dosing and formulations.

Major clinical guidelines do not currently recommend CoQ10 as a standard treatment for muscular dystrophy due to the lack of robust, large-scale randomized controlled trials. However, CoQ10 is sometimes used as an adjunctive treatment in clinical practice because of its good safety profile and theoretical rationale. In summary, while there is some scientific rationale and preliminary clinical evidence supporting CoQ10 use in muscular dystrophy, the evidence is weak (rated 2/5), and further research is needed to confirm its efficacy.

More about coenzyme Q10 (CoQ10)
More about Muscular Dystrophy

Other ingredients used for Muscular Dystrophy

Acetyl L-carnitine
coenzyme Q10 (CoQ10)
creatine monohydrate
turmeric
omega-3 fatty acids
Urolithin A
vitamin D
Arginine Creatine
Creatine
HMB Hydroxymethylbutyrate
Phosphocreatine

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Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Muscular Dystrophy

Table of Contents

Synopsis

Other ingredients used for Muscular Dystrophy

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Health Concerns

Brands

Evidence supporting the use of: Coenzyme Q10 (CoQ10)For the health condition: Muscular Dystrophy

Table of Contents

Synopsis

Other ingredients used for Muscular Dystrophy

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Muscular Dystrophy