Proprietary blends of herbs and botanicals have a long history of traditional use for supporting nail health, primarily in systems of medicine such as Ayurveda, Traditional Chinese Medicine (TCM), and Western herbalism. Common ingredients found in these blends may include horsetail (Equisetum arvense), nettle (Urtica dioica), and bamboo, all of which are traditionally believed to strengthen nails due to their silica or mineral content. Other botanicals like burdock root and dandelion are sometimes included for their reputed ability to "cleanse" or "nourish" the blood, which is believed in some traditions to reflect in stronger, healthier nails.

However, while these uses are well-established in traditional contexts, scientific validation is limited. Some in vitro and animal studies suggest that certain minerals (like silica) and phytochemicals in these plants may play a role in connective tissue health, but high-quality human trials directly linking proprietary herbal blends to improved nail strength or growth are lacking. Most evidence supporting these blends for nail health is anecdotal or based on traditional use rather than rigorous clinical trials. As such, the justification for their use is predominantly traditional, and the evidence rating is relatively low.