Evidence supporting the use of: Asarum heterotropoides
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Asarum heterotropoides, commonly known as wild ginger or "Xi Xin" in Traditional Chinese Medicine (TCM), has a long history of use in East Asian herbal traditions, including for symptoms like nausea and vomiting. In TCM, Xi Xin is thought to "dispel cold," "open the nasal passages," and "alleviate pain," and is often incorporated into multi-herb formulas aimed at treating various conditions, including digestive discomfort and nausea. The traditional rationale is largely based on empirical use and theoretical frameworks unique to TCM, rather than on modern pharmacological understanding.

There is limited scientific research directly validating the antiemetic (anti-nausea) effects of Asarum heterotropoides. Some preclinical studies have identified volatile oils and aristolochic acids within the plant, which may have pharmacological activity. However, these studies are sparse, not specifically focused on nausea/vomiting, and are mostly limited to animal models or in vitro experiments. Additionally, safety concerns—particularly related to aristolochic acid's nephrotoxicity—have limited the scope of clinical investigation.

In summary, the use of Asarum heterotropoides for nausea and vomiting is primarily supported by traditional use rather than robust scientific evidence. The evidence rating is moderate for traditional use (2 out of 5) but remains weak for scientific validation. Caution is warranted due to potential toxicity.

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