Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Doxylamine succinate is scientifically validated for use in treating nausea and vomiting during pregnancy, particularly in combination with pyridoxine (vitamin B6). This specific combination is the active component in the FDA-approved medication Diclegis (in the U.S.) and Diclectin (in Canada), which are indicated for the management of nausea and vomiting of pregnancy (NVP) when conservative management fails. The evidence for this use is robust, stemming from multiple randomized controlled trials and decades of clinical experience, beginning with the use of a similar formulation (Bendectin) in the 1950s. Systematic reviews and meta-analyses have confirmed the efficacy and safety of doxylamine/pyridoxine for NVP, with a favorable risk profile, including no increased risk of birth defects. The American College of Obstetricians and Gynecologists (ACOG) and other professional bodies recommend this combination as a first-line pharmacologic therapy for NVP. However, it is important to note that doxylamine succinate alone (without pyridoxine) is not generally studied or used for nausea and vomiting outside of pregnancy, and its use for other causes of nausea is not supported by significant evidence. In summary, doxylamine succinate (with pyridoxine) is a scientifically validated and guideline-recommended treatment for nausea and vomiting of pregnancy.

More about Doxylamine succinate
More about Nausea and Vomiting

Other ingredients used for Nausea and Vomiting

Agarwood
Agastache
Agrimonia pilosa
Allspice
alpinia galangal
Amomum
Amor seco
Angostura
anise
apple cider vinegar
arrowroot
asafoetida
Asam gelugor
Asarum heterotropoides
Asarum sieboldii
atractylodes
atractylone
Baccharoides anthelmintica
bael
bai ji
balloon flower
balsam
bamboo
banana
banyan
benegut perilla (proprietary)
betel
bitter principals
Black Hellebore
black nightshade
black pepper
black salt
black seed
blue flag
Borassus aethiopum
bottle gourd
Bryonia
Buddha\'s hand
buttermilk
butternut
calamus
Camellia sinensis
camphor oil
cannabidiol
caraway
cardamom
carvone
centaury
chamomile
chen pi
chickweed
Chinese silkvine
chirata
chrysanthemum
cinquefoil
citron
Clerodendrum trichotomum
coca
cola nut
colocynth
Coptis chinensis
coriander
cubeb
cumin
Cyathula
Cymbopogon martini
dill
dioscorea
dogwood
Doxylamine succinate
elephant\'s head
Embelia
English horsemint
Evodia
false calumba
fennel
fenugreek
fernbush
flowering quince
gentian
Gentianella alborosea
Gentianopsis barbata
giant blazingstar
ginger
goldthread
gooseberry
Hedychium spicatum
Homalomena
horehound
hyssop
Indian ipecac
Javanese Long Pepper
jujube
kola nut
kudzu
Kukicha
Large-leaf gentian
Large-leaved linden
Lesser speargrass
licorice root
lime
linden
little ironweed
loquat
lotus
lovage
mace
Malva sylvestris
mandarin
Marjoram
Marsh Tea
Matapalo Tree
Meadowsweet
Mentha haplocalyx
Mint
Myrobalan
Nardostachys
Natsudaidai
Ophiopogon
orange
Osmanthus
peach
Pepper Bark Tree
Peppermint
Persimmon
Phragmites
Phthalides
phytocannabinoids
Pimpinella
Piper chaba
Piper retrofractum
Plectranthus amboinicus
Polygonatum
prickly ash
Pulsatilla
quince
Rhus coriaria
root tuber
rose
Rubiaceae
Rubus
rue
sage
Sassafras
Savory
Scabrous Gentian
sea salt
Sensitive Plant
Sichuan pepper
soursop
Southernwood
spearmint leaf
Stephania root
Sweet Bay
Sweet Orange alcohol
sweetgums
Swertia
Szechuan lovage
Tarragon
typhonium
Vanilla
Vervain
vitamin B6
Watermelon
Yellow Nut Sedge
Yerba mate
Yuzu

Other health conditions supported by Doxylamine succinate

Insomnia
Morning Sickness
Nausea and Vomiting
Sleep (restless and disturbed)

Products containing Doxylamine succinate

We currently have no products on Vitabase that contain this ingredient.