Evidence supporting the use of: Little ironweed
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Little ironweed (Vernonia cinerea) has a history of use in traditional medicine systems, particularly in parts of Asia, for a variety of ailments including nausea and vomiting. In traditional Thai and Indian medicinal practices, decoctions or extracts of the plant have been used to manage digestive disturbances, including the control of nausea and vomiting. The rationale for its use is based primarily on empirical observations passed down through generations rather than on rigorous scientific validation. Scientific studies on Vernonia cinerea have focused more on its anti-inflammatory, anti-helminthic, and antioxidant properties, as well as its use in smoking cessation and diabetes management. There is a lack of high-quality clinical trials or pharmacological investigations specifically evaluating its efficacy for nausea and vomiting. Some phytochemical analyses show the presence of compounds such as flavonoids and sesquiterpene lactones, which may have biological activities, but these have not been directly linked to antiemetic effects in clinical contexts. In summary, Little ironweed’s use for nausea and vomiting is primarily justified by traditional practices rather than strong scientific evidence, and the overall quality of supporting evidence is low.

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