Mace (the dried aril of the nutmeg seed, Myristica fragrans) has a long history of use in traditional medicine systems such as Ayurveda and Unani. In these systems, mace has been employed to support digestion and to help manage symptoms like nausea, vomiting, and flatulence. The rationale for its traditional use centers around its warming and carminative properties, which are believed to soothe the digestive tract and reduce gastrointestinal discomfort.

However, when it comes to scientific validation, evidence supporting the effectiveness of mace specifically for nausea and vomiting is extremely limited. Most available studies on Myristica fragrans focus on its general antioxidant, anti-inflammatory, or antimicrobial properties, or on nutmeg rather than mace itself. There are no high-quality clinical trials or substantial pharmacological studies directly assessing mace’s efficacy for nausea or vomiting. Therefore, while traditional use is well documented, the evidence supporting its use for this indication is weak and primarily anecdotal.

In summary, mace's use for nausea and vomiting is rooted in traditional practices rather than scientific research, and the strength of the supporting evidence is low.