Evidence supporting the use of: Missouri Snakeroot
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Missouri Snakeroot (commonly referring to Aristolochia serpentaria or Polygala senega, though the name has been applied to several plants) has a history of traditional use by Native Americans and early European settlers for a variety of ailments, including nausea and vomiting. Historical records indicate that Native American tribes brewed teas or decoctions from the root as an emetic (to induce vomiting), and as a remedy for snakebite, respiratory issues, and digestive complaints. Early American herbalists also adopted its use, citing its stimulating and expectorant effects. However, there is a lack of modern scientific studies evaluating the efficacy or safety of Missouri Snakeroot for the treatment of nausea and vomiting. No controlled clinical trials or pharmacological investigations have validated its historical uses for these indications. In addition, some species referred to as "snakeroot" contain potentially toxic compounds, and their use is discouraged due to safety concerns. Therefore, while the use of Missouri Snakeroot for nausea and vomiting is primarily justified by tradition, the evidence supporting its effectiveness is limited to anecdotal and historical sources, and modern scientific validation is lacking.

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