Evidence supporting the use of: Phthalides
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Phthalides are a group of naturally occurring compounds most notably found in plants such as celery (Apium graveolens) and Ligusticum species (e.g., Ligusticum chuanxiong, a traditional Chinese medicinal herb). Their use for nausea and vomiting is primarily rooted in traditional medicine systems, particularly Traditional Chinese Medicine (TCM). In TCM, herbs containing phthalides, such as Chuanxiong, are often included in formulations to "regulate qi" and alleviate various symptoms, including digestive disturbances like nausea. However, the rationale is based on holistic and empirical approaches rather than on isolated pharmacological effects of phthalides themselves. Modern scientific validation specifically linking phthalides to antiemetic (anti-nausea and vomiting) effects remains limited. Most research on phthalides focuses on their vascular, neuroprotective, or anti-inflammatory properties. Few preclinical studies have explored their effects on gastrointestinal motility, but direct evidence for their use in treating nausea and vomiting in humans is lacking. As a result, the support for using phthalides for these symptoms is considered traditional, and the evidence level is low, reflecting the absence of robust clinical trials or mechanistic studies to confirm their efficacy.

More about Phthalides
More about Nausea and Vomiting

Other ingredients used for Nausea and Vomiting

Allspice
bamboo
Myrobalan
benegut perilla (proprietary)
betel
black pepper
chamomile
chen pi
Coptis chinensis
fennel
fenugreek
ginger
gooseberry
jujube
kudzu
licorice root
lovage
Mint
orange
Peppermint
phytocannabinoids
sage
spearmint leaf
vitamin B6
Watermelon
chickweed
tangerine
typhonium
hyssop
cardamom
atractylodes
alpinia galangal
Hedychium spicatum
anise
Swertia
Szechuan lovage
prickly ash
root tuber
chrysanthemum
flowering quince
dogwood
dioscorea
sweetgums
caraway
camphor oil
Yerba mate
peach
horehound
Sichuan pepper
soursop
sea salt
apple cider vinegar
Agastache
Amomum
Asarum heterotropoides
asafoetida
Agarwood
Asam gelugor
Angostura
arrowroot
Agrimonia pilosa
Amor seco
Asarum sieboldii
atractylone
black seed
buttermilk
blue flag
Bryonia
bai ji
balsam
bael
butternut
Baccharoides anthelmintica
banyan
black salt
back nightshade
Buddha\'s hand
Borassus aethiopum
bitter principals
banana
Black Hellebore
balloon flower
bottle gourd
cumin
centaury
Camellia sinensis
Chinese silkvine
Clerodendrum trichotomum
coriander
cinquefoil
Cyathula
citron
carvone
Cymbopogon martini
coca
cubeb
chirata
cannabidiol
calamus
colocynth
cola nut
dill
Doxylamine succinate
Evodia
English horsemint
elephant\'s head
Embelia
fernbush
false calumba
goldthread
gentian
Gentianella alborosea
Gentianopsis barbata
giant blazingstar
Homalomena
Indian ipecac
Javanese Long Pepper
Kukicha
kola nut
loquat
lime
Large-leaf gentian
Lesser speargrass
linden
lotus
Large-leaved linden
little ironweed
Mentha haplocalyx
mandarin
Marjoram
Marsh Tea
mace
Malva sylvestris
Matapalo Tree
Meadowsweet
Nardostachys
Natsudaidai
Ophiopogon
Osmanthus
Phragmites
Piper chaba
Pulsatilla
Pepper Bark Tree
Phthalides
Piper retrofractum
Polygonatum
Pimpinella
Persimmon
Plectranthus amboinicus
quince
rue
Rubus
Rubiaceae
rose
Rhus coriaria
Stephania root
Sensitive Plant
Southernwood
Savory
Scabrous Gentian
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Vanilla
Yuzu
Yellow Nut Sedge

Products containing Phthalides

We currently have no products on Vitabase that contain this ingredient.