Pimpinella, commonly known as anise (Pimpinella anisum), has a long history of use in traditional herbal medicine systems, particularly in Europe, the Middle East, and parts of Asia. Traditional healers and folk medicine practitioners have recommended anise seeds and their preparations for a variety of digestive complaints, including nausea and vomiting. The rationale is largely based on the carminative and spasmolytic properties ascribed to the essential oils found in anise, which are believed to soothe the gastrointestinal tract and relieve symptoms like bloating, indigestion, and mild nausea. Some traditional texts and ethnobotanical surveys mention the use of anise tea or extracts for calming the stomach and reducing discomfort after meals.

However, there is very limited scientific evidence directly supporting the use of Pimpinella anisum for the treatment of nausea and vomiting in humans. Most modern research focuses on its antimicrobial, antioxidant, and mild spasmolytic effects, with only a few preclinical or small clinical studies addressing gastrointestinal symptoms, and even fewer specifically targeting nausea or vomiting. Thus, while its use for this purpose is well-documented in traditional contexts, contemporary clinical validation is lacking, justifying a low evidence rating.