Evidence supporting the use of: Scabrous Gentian
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Scabrous Gentian (Gentiana scabra) is primarily used in traditional East Asian medicine to address digestive complaints, including nausea and vomiting. In Traditional Chinese Medicine (TCM), Scabrous Gentian (known as "Long Dan Cao") is valued for its bitter properties and is said to "clear heat" and "dry dampness," actions believed to support liver and gallbladder health and alleviate symptoms like nausea. The traditional use is documented in TCM pharmacopeias and herbal texts, which recommend Gentiana scabra in formulas for conditions presenting with nausea, vomiting, and digestive upset, especially when associated with "damp-heat" syndromes.

However, the scientific evidence supporting these uses is limited. While there are studies on gentian species suggesting general digestive benefits (such as stimulation of gastric secretions), rigorous clinical trials specifically investigating Gentiana scabra for nausea or vomiting are lacking. Most support for its antiemetic use comes from historical practice and anecdotal reports rather than controlled scientific studies. Thus, its use for nausea and vomiting remains justified primarily by traditional practice, with only modest indirect pharmacological support.

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