Evidence supporting the use of: Aerva lanata
For the health condition: Nephritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Aerva lanata, commonly known as "Mountain Knotgrass," has been traditionally used in Ayurvedic and other traditional medicine systems for the management of nephritis and other kidney-related ailments. Historical texts and ethnobotanical surveys document its use as a diuretic and as a remedy for urinary tract disorders, including nephritis, which is inflammation of the kidneys. The plant is reputed to promote urinary output and reduce inflammation, which are relevant actions for supporting kidney health in traditional frameworks.

Scientific investigation into Aerva lanata's effects on nephritis is limited. Some in vitro and animal studies indicate potential nephroprotective effects, likely due to antioxidant and anti-inflammatory constituents such as flavonoids and alkaloids. However, these studies are preliminary, often conducted in animal models or cell cultures, and direct clinical trials in humans are lacking. No robust, high-quality human trials have established its efficacy or safety for nephritis. Thus, while traditional use is well documented and partially supported by early pharmacological evidence, the overall scientific validation remains insufficient.

In summary, Aerva lanata is traditionally used for nephritis, and there is some experimental support for its potential renal benefits, but strong scientific evidence in humans is absent.

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