Evidence supporting the use of: Licorice root
For the health condition: Nephritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, including Traditional Chinese Medicine (TCM) and Ayurveda, where it has been used to support kidney health and address symptoms associated with nephritis (inflammation of the kidneys). In TCM, licorice is regarded as a harmonizing herb and is believed to "clear heat and toxin," which includes conditions interpreted as nephritic syndromes. Historically, it has been used to reduce inflammation, relieve pain, and promote healing in the urinary tract and kidneys.

However, modern scientific evidence supporting licorice root’s efficacy in treating nephritis is limited. Some studies suggest licorice may have anti-inflammatory and immunomodulatory properties, potentially offering some benefit in inflammatory kidney conditions. The active compound glycyrrhizin has shown renal protective effects in animal studies, but these effects have not been conclusively demonstrated in humans with nephritis. Furthermore, excessive licorice consumption can lead to serious side effects, including hypertension, hypokalemia, and even worsening kidney function.

In summary, while licorice root’s use for nephritis is primarily rooted in traditional medicine, the scientific evidence remains minimal and largely preclinical. Anyone considering licorice for kidney conditions should consult a healthcare professional due to potential adverse effects.

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Other health conditions supported by licorice root

Abdominal Pain
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