Evidence supporting the use of: Lophatherum
For the health condition: Nephritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lophatherum gracile (commonly known as "Dan Zhu Ye" in traditional Chinese medicine) has a long history of use in East Asian herbal medicine. Historically, it has been used primarily as a diuretic, to clear heat, and to promote urination, which indirectly links it to treating conditions associated with the urinary system, such as nephritis (inflammation of the kidneys). Classical Chinese medical texts recommend Lophatherum for symptoms like difficult urination, irritability, and mouth sores, which are sometimes interpreted as manifestations of internal heat affecting the urinary tract.

However, the evidence supporting its use for nephritis is grounded primarily in traditional practice, not in robust scientific validation. While some pharmacological studies have shown that Lophatherum extracts may exert mild anti-inflammatory and diuretic effects in animals, there is a lack of high-quality clinical trials in humans specifically evaluating its efficacy for nephritis or related kidney disorders. Thus, its use for nephritis is justified by historical precedent and traditional formulations rather than by rigorous modern scientific evidence.

In summary, Lophatherum's use in nephritis is rooted in traditional medicine, with limited experimental data and no strong clinical research to confirm its effectiveness for this specific condition.

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