Evidence supporting the use of: Mulberry
For the health condition: Nephritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mulberry (Morus alba) has a long history of use in traditional medicine systems, particularly in East Asia, for supporting kidney health, including conditions like nephritis (inflammation of the kidneys). In Traditional Chinese Medicine (TCM), various parts of the mulberry plant—leaves, fruit, and root bark—are believed to nourish yin, clear heat, and promote diuresis, which are thought to be beneficial for kidney-related ailments. The root bark (Sang Bai Pi) is especially noted in classical texts for its purported ability to reduce swelling and treat urinary difficulties, symptoms sometimes associated with nephritis.

However, scientific evidence directly supporting the use of mulberry for nephritis in humans is limited. Some preclinical studies suggest that mulberry extracts possess anti-inflammatory, antioxidant, and nephroprotective properties. For instance, animal studies have demonstrated that mulberry extracts may reduce markers of kidney inflammation and oxidative stress. Nevertheless, these findings have not been robustly translated into large-scale clinical trials in humans with nephritis. Therefore, while mulberry is traditionally used for kidney health, modern scientific validation for its effectiveness in treating nephritis is lacking. Most recommendations for its use in nephritis are based on historical precedent rather than rigorous clinical evidence.

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