Evidence supporting the use of: Reishi mushroom
For the health condition: Nephritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum), known as "Lingzhi" in traditional Chinese medicine (TCM), has been used for centuries as a general health tonic and for its purported effects on the immune system and kidney health. The traditional use of reishi for nephritis (kidney inflammation) is rooted in TCM, where it is considered to nourish the kidneys, strengthen Qi, and promote the body's resistance to illness. Reishi is often prescribed in TCM formulas for individuals with kidney-related ailments, including nephritis and chronic kidney disease. From a scientific perspective, there is limited but emerging evidence of its potential renoprotective effects. Preclinical studies (in vitro and animal models) suggest that reishi extract may have anti-inflammatory, immunomodulatory, and antioxidant properties, which could theoretically be beneficial in conditions like nephritis, where inflammation and immune dysfunction play significant roles. Some animal studies have shown that reishi extracts can reduce markers of kidney inflammation and injury. However, well-controlled human clinical trials are lacking, and there is insufficient direct evidence to conclusively support its use for nephritis in humans. In summary, the primary justification for using reishi mushroom in nephritis comes from traditional medical systems, with only modest preclinical scientific support and a lack of robust clinical evidence. Individuals considering reishi for nephritis should consult healthcare professionals due to possible interactions and the need for more definitive research.

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