Evidence supporting the use of: Guelder rose
For the body system: Nerves
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Guelder rose (Viburnum opulus) has a long history of traditional use in herbal medicine, particularly for its supposed calming and antispasmodic effects, which are believed to support the nervous system. In folk medicine, especially in Europe and North America, guelder rose bark (often called "cramp bark") has been used to help alleviate muscle spasms, menstrual cramps, and nervous tension. The bark contains compounds such as valerenic acid, coumarins, and various tannins, which are thought to impart mild sedative and muscle-relaxant properties. However, these effects are largely based on traditional applications and anecdotal reports rather than robust clinical studies.
Scientific research on the direct effects of guelder rose on the nervous system is limited. Most available studies focus on its antispasmodic properties, with some in vitro and animal studies suggesting that extracts may help relax smooth muscle. There is little direct evidence from human trials to confirm its efficacy for supporting the nervous system specifically. Thus, while its use for nervous system support is justified by tradition, scientific validation remains weak, and the overall quality of evidence is low. Caution is advised due to the lack of high-quality human studies.
Other ingredients that support Nerves
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7,8-Dihydroxyflavone
Acetyl L-carnitine
Acetyl-L-Tyrosine
Acetylcholine
Aconite
Agarwood
Agmatine
Albizia
Alfalfa
algal oil
Almond fruit
Alpha glyceryl
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
anchovies
Anemone
Angelica
animal protein
Anserina
antler
apigenin
arachidonic acid
Aralia
ashitaba
ashwagandha
asiaticoside
avens
avocado
baccosides
Bacopa
Bacopin
bacoside
baicalein
baicalin
Baikal Skullcap
banana
basil
bee products
bee venom
beef
Beef liver
benfotiamine
beta caryophyllene
betel
betony
bilobalide
biopterin
black cohosh
black galingale
black ginger
black gram
Black Hellebore
Black willow
bleeding heart
borneol
bovine liver
brahmi
Brazil nut
broad bean
broccoli
bugbane
bасора
caffeine
calamari oil
calamus
calcium
Calea zacatechichi
California poppy
camphor oil
canadine
cannabichromene
cannabidiol
cannabigerol
Cannabis sativa oil
Canscora
Capitate Valerian
capsaicin
caryophyllene
catalpol
catecholamine
catnip
catuaba
Celastrus
Centella asiatica
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centrophenoxine
chamomile
Chinese mountain ant
chloride
chocolate
choline
chuchuhuasi
citicoline
Clary sage
Clerodendrum trichotomum
coca
cocarboxylase
cocoa
coconut
cod liver oil
coenzyme Q10 (CoQ10)
cola nut
Convolvulus pluricaulis
Convolvulus prostratus
copper
cordyceps
Corydalis
cowage seed
cowslip
cramp bark
Curcuma
Curcuminoid
Cymbidium goeringii
cytidine
d-alpha tocopherol
D-phenylalanine
damiana
date
deanol
deer velvet
Dendrobium
DHA (docosahexaenoic acid)
Dicentra formosa
dihydrolipoic acid
diterpenes
DMPX
docosahexaenoic Acid
dopamine
DPA (docosapentaenoic acid)
dwarf morning glory
egg
electrolytes blend (proprietary)
eleuthero
ergothioneine
Erythrina
essential oil blend
eucommia
fatty acids
feverfew
fibroblast growth factor
fish
fish oil
fish protein
flavin mononucleotide
flavones
flavonols
fo-ti
folate
folic acid
fungus
GABA (gamma aminobutyric acid)
galantamine
gamma linolenic acid (GLA)
gastrodia
gastrodin
Gelsemium
ginger
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
ginseng
Ginsenosides
glucose
Glutamic acid
glycerophosphocholine (GPC)
Glycine
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gotu kola
Griffonia simplicifolia
guarana
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guayusa
guelder rose
hazelnut
heal-all
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hemp
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hops
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hyperforin
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inositol
iron
isobutylamides
jasmine
Jatamansi
jujube
jujubosides
kanna
kava
kavalactones
kola nut
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-carnitine
L-glycine
L-phenylalanine
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L-theanine
L-tryptophan
l-tyrosine
lactium casein decapeptide
Lactucarium
Large-leaved linden
Lavandin
lavender
lecithin
Legume protein
lemon balm
Ligusticum
ligustilides
linalool
linden
lingzhi
lion's mane
lipids
lobelia
longan
lotus
lupulinum
magnesium
magnolia
magnolol
mandrake
manganese
maral root
Marine fat
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Marking Nut Tree
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Morinda
Motherwort
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Muira puama
Mulungu
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Myrcene
N-acetyl leucine
NADH
Nardostachys
Nervonic acid
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
Nigella seed
noni
Nutmeg
oat
olive
omega-3 fatty acids
oriental arborvitae
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
pantothenic acid (vitamin B5)
passionflower
Pea
peony
Peppermint
Phenylpropanoids
phosphatidylcholine
Phosphatidylethanolamine
phosphatidylserine
phospholipids
phosphorus
phytocannabinoids
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Polygala
polygala root
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polyphenols
polyunsaturated fat
poppy
Portulaca
potassium
prepared aconite tuber
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Propionyl-L-Carnitine
protein
Puerain
Puerarin
Pulsatilla
Purple Monkeyflower
purslane
pyridoxal-5-phosphate (P-5-P)
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pyrroloquinoline quinone
Rauvolfia
reishi mushroom
relora® (proprietary)
Rhodiola
robusta coffee
Rosarin
rosavins
rose
rose oil
rosemary
royal jelly
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rue
Safed musli
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Safranal
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Salidroside
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SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
sceletium
Schisandrins
Schizandrol A
Schizochytrium
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Sedanenolide
Sensitive Plant
sesame
Shankhpushpi
Shilajit
Sichuan Lovage
Sichuan pepper
Sida cordifolia
silk tree
skullcap
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Southern Tsangshu
spearmint leaf
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
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velvet bean
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Walnut
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Xylaria nigripes
Yarrow
Yeast
Yerba mate
Ylang ylang
Yohimbe
Yohimbine
zanthoxylum
Zinc
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Other body systems supported by guelder rose
BladderDigestive System
Female Reproductive System
Muscles
Nerves
Reproductive System
Uterus
