Evidence supporting the use of: Polyphenols (npt specified)
For the body system: Nerves

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols are a diverse group of naturally occurring compounds found primarily in plants, including fruits, vegetables, tea, coffee, and cocoa. There is growing scientific evidence supporting their neuroprotective properties and potential to support the nervous system. Polyphenols have been shown in preclinical studies to exert antioxidant and anti-inflammatory effects, which are important in protecting neurons from oxidative stress and neuroinflammation—two key contributors to neurodegenerative diseases such as Alzheimer's and Parkinson's.

Several human observational studies and a limited number of clinical trials have associated diets high in polyphenols (such as the Mediterranean diet) with a reduced risk of cognitive decline and improved cognitive performance. Mechanistic research suggests that polyphenols may modulate signaling pathways involved in neuronal survival, synaptic plasticity, and neurogenesis. For example, flavonoids (a subclass of polyphenols) found in berries and cocoa have been shown to improve memory and learning in animal models and may enhance cerebral blood flow in humans.

However, while the evidence base is promising, it is not yet conclusive. Many studies are observational, and intervention trials often use mixed sources or extracts, making it challenging to pinpoint specific effects. Nonetheless, the overall scientific consensus is that polyphenols have a potential supportive role for the nervous system, particularly due to their antioxidant and anti-inflammatory properties.

More about Polyphenols (npt specified)
More about Nerves

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Products containing Polyphenols (npt specified)

We currently have no products on Vitabase that contain this ingredient.