Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amino acids, the building blocks of proteins, have been explored for their potential role in supporting nervous system health and addressing symptoms often described as "nervous exhaustion"—a term historically associated with fatigue, stress, and burnout, sometimes referred to as neurasthenia. Scientifically, some amino acids such as L-tryptophan, L-tyrosine, and L-theanine have been researched for their effects on neurotransmitter synthesis (e.g., serotonin, dopamine, GABA), which are implicated in mood regulation, stress response, and mental fatigue. For example, L-tryptophan supplementation can increase serotonin levels, potentially improving mood and decreasing symptoms of fatigue and anxiety. L-tyrosine is a precursor to dopamine and norepinephrine, and some studies suggest it may help mitigate the effects of acute stress and improve cognitive performance in stressful situations. However, while these mechanisms are plausible and some trials show benefit in acute stress or mild depressive states, robust clinical evidence supporting the use of amino acids specifically for "nervous exhaustion" is limited. Most data come from small studies, and the condition itself is not well-defined in modern clinical terms. Thus, the overall evidence is weak to moderate (rated 2/5), with more support for targeted symptoms (such as fatigue or stress) than for the broader, less-specific diagnosis of nervous exhaustion. Amino acids are not typically first-line treatments for this condition, and further research is needed to fully establish their efficacy.

More about amino acids
More about Nervous Exhaustion

Other ingredients used for Nervous Exhaustion

Other health conditions supported by amino acids

Products containing amino acids

Douglas Laboratories Free Form Amino