Evidence supporting the use of: Eleutheroside
For the health condition: Nervous Exhaustion

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Eleutheroside, the primary active constituent found in Eleutherococcus senticosus (Siberian ginseng), has been traditionally used in Russian and East Asian herbal medicine to address "nervous exhaustion," a term historically used to describe symptoms of fatigue, stress, and reduced mental performance. The traditional application is based on the concept of "adaptogenic" herbs, which are believed to help the body resist physical, chemical, and biological stressors. In this context, Siberian ginseng has been used to combat fatigue and improve resilience in stressful situations, including convalescence from illness and mental overwork.

Scientific studies have explored the adaptogenic properties of Eleutherococcus senticosus and its eleutherosides, with some clinical trials indicating possible benefits in reducing fatigue and improving certain cognitive performance parameters. However, the evidence is limited and often methodologically weak, with inconsistent results and small sample sizes. Systematic reviews generally conclude that while there is some support for traditional claims, the quality and quantity of research do not allow for definitive scientific validation, especially regarding the specific use for "nervous exhaustion." As such, its use for this condition remains primarily justified by traditional knowledge rather than strong scientific evidence.

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