Evidence supporting the use of: Ginseng, American
For the health condition: Nervous Exhaustion

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

American Ginseng (Panax quinquefolius) has a long history of use in traditional herbal medicine, particularly among Native American tribes and later in Western herbalism, for conditions associated with "nervous exhaustion"—a term historically used to describe symptoms like fatigue, weakness, and mental burnout. Traditionally, American Ginseng has been valued as a general tonic and adaptogen, believed to help the body cope with stress and restore vitality. Documentation from 19th and early 20th-century herbal texts often lists American Ginseng as a remedy for nervous conditions, debility, and overwork, though these uses were based on empirical observation rather than controlled studies.

Modern scientific research on American Ginseng has focused primarily on its potential to improve cognition, reduce fatigue, and enhance general well-being, but studies are limited and results are mixed. There is some evidence that it may reduce fatigue in cancer patients and improve certain cognitive parameters, but direct clinical research specifically targeting "nervous exhaustion" as a defined syndrome is lacking. As such, while there is a strong tradition of use for this purpose, scientific validation remains limited, and the evidence quality is low to moderate (rated 2/5). Most contemporary discussions of American Ginseng's benefits for nervous exhaustion still reference its traditional use rather than robust clinical data.

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