Evidence supporting the use of: Gland (mixed)
For the health condition: Nervous Exhaustion

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Gland (mixed), often found in traditional "glandular therapy" or "protomorphogen" supplements, refers to desiccated extracts of various animal glands (such as adrenal, thyroid, pituitary, etc.). Its use for conditions like "nervous exhaustion" (an older term roughly corresponding to what we might now call chronic fatigue, burnout, or neurasthenia) is primarily based on historical medical practices, especially from the late 19th to early 20th centuries. During this time, some physicians theorized that supplementing with animal gland extracts could "rejuvenate" or support the corresponding human glands, thereby improving symptoms attributed to glandular weakness or fatigue. There is little to no modern scientific validation for these claims. Most evidence comes from anecdotal reports and early clinical case studies, often lacking control groups or rigorous methodology. The rationale behind their use was rooted in the "doctrine of signatures" and early endocrinology, not in controlled trials or biochemical evidence. Modern medicine generally does not support the use of mixed glandular extracts for nervous exhaustion, as there is no reliable evidence that oral glandulars can survive digestion in a form that significantly affects human endocrine function. Regulatory agencies and professional organizations do not endorse their use for this or related conditions. Thus, the practice persists largely as a historical or alternative medicine tradition rather than an evidence-based therapy.

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Other health conditions supported by Gland (mixed)

Adrenal Fatigue
Anemia
Convalescence
Nervous Exhaustion
Post Partum Weakness

Products containing Gland (mixed)

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