Evidence supporting the use of: Henbane
For the health condition: Neuralgia and Neuritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Henbane (Hyoscyamus niger) has a long history of use in traditional medicine as an analgesic and sedative, particularly in the management of pain conditions, including neuralgia and neuritis. Ancient Greek, Roman, and various European herbal traditions described the use of henbane preparations for their antispasmodic and pain-relieving effects. The plant contains tropane alkaloids such as hyoscyamine, scopolamine, and atropine, which have recognized pharmacological actions on the nervous system, including anticholinergic and analgesic properties. Historically, henbane was sometimes incorporated into poultices, tinctures, or smoked for nerve pain; however, its use was always tempered by concerns about toxicity and unpredictable dosing. Despite this traditional usage, there is little to no robust scientific evidence from modern clinical trials or pharmacological studies supporting the efficacy or safety of henbane specifically for neuralgia or neuritis. The risk of severe side effects, including hallucinations, anticholinergic syndrome, and even death, has led to its disuse in contemporary evidence-based medicine. In summary, while henbane’s application for neuralgia and neuritis is documented in traditional medical texts and herbal pharmacopeias, its use is not validated by modern scientific research, and significant safety concerns remain.

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