Evidence supporting the use of: Bacoside
For the health condition: Neurosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacoside, the active constituent of Bacopa monnieri (commonly known as Brahmi), is primarily supported by scientific evidence for cognitive enhancement, neuroprotection, and anxiolytic effects, rather than for the treatment of neurosis per se. Neurosis is an outdated psychiatric term that generally refers to non-psychotic mental disorders characterized by anxiety, depression, or other distressing symptoms without loss of contact with reality. While bacosides have been shown in several preclinical and limited clinical studies to exert anxiolytic and adaptogenic (stress-resistance) effects, direct evidence for their efficacy specifically in "neurosis" is sparse due to the broad and somewhat obsolete nature of the term in modern medicine.

Nevertheless, studies have demonstrated that Bacopa extracts can modulate neurotransmitter systems, reduce anxiety-like behaviors in animal models, and improve stress adaptation, which are relevant to the symptomatic treatment of anxiety and related conditions. Some small-scale clinical trials have reported reduced anxiety and improved mood in healthy adults and patients with mild anxiety symptoms after Bacopa supplementation. However, rigorous, large-scale clinical trials targeting defined neurotic disorders are lacking, and most existing evidence is preliminary. Thus, while there is a scientific rationale and early-stage evidence supporting the use of bacosides for symptoms common to neurosis (particularly anxiety and stress), the overall quality and quantity of evidence remain limited, justifying a moderate-low rating.

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Products containing bacoside

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