Evidence supporting the use of: Passionflower
For the health condition: Neurosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Passionflower (Passiflora incarnata) has a long history of traditional use as a calming herb for various nervous conditions, including what was historically termed "neurosis" (now more commonly described as anxiety, insomnia, or related mood disorders). Several modern studies have investigated its anxiolytic (anxiety-reducing) properties. Some small clinical trials suggest that passionflower extracts may have modest benefits in reducing anxiety symptoms, often compared favorably to pharmaceutical anxiolytics such as oxazepam in the short term. The proposed mechanism involves modulation of the gamma-aminobutyric acid (GABA) system, leading to central nervous system relaxation. However, the overall quality of the scientific evidence is moderate to low. Many studies have small sample sizes, short durations, and methodological limitations. Systematic reviews and meta-analyses note the need for larger, high-quality trials to confirm efficacy and safety. Despite these limitations, passionflower is commonly included in herbal preparations for anxiety and related conditions, and it is approved by some European regulatory agencies (e.g., German Commission E) for "nervous restlessness." In summary, while passionflower's use for neurosis (anxiety symptoms) is supported by both tradition and some scientific evidence, the strength of scientific validation is limited (rating: 2/5). It may be considered as a complementary approach, but should not replace evidence-based psychiatric treatments where indicated.

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