Evidence supporting the use of: Schisandrins
For the health condition: Neurosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Schisandrins are lignans extracted from the fruit of Schisandra chinensis, a plant commonly used in traditional Chinese medicine (TCM). Historically, Schisandra and its active components have been employed in TCM for their reputed adaptogenic, sedative, and neuroprotective effects. In the context of neurosis—a broad term historically used to describe various nervous disorders characterized by anxiety, irritability, or emotional instability—Schisandra has been included in herbal formulations aimed at calming the mind, alleviating stress, and improving mental clarity. Traditional texts cite its use for "calming the spirit" and "relieving palpitations and insomnia," symptoms that overlap with certain neurotic presentations. Scientific research into Schisandrins does suggest neuroprotective and anti-fatigue properties, and some animal studies have demonstrated anxiolytic-like effects. However, there is only limited direct clinical research specifically addressing the efficacy of Schisandrins for neurosis as defined in Western medicine. The bulk of evidence comes from traditional usage and small-scale studies that may not meet rigorous clinical standards. As such, while there is a historical precedent for using Schisandrins in the management of symptoms associated with neurosis, robust scientific validation is lacking, and current evidence remains preliminary.

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