Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amino acids have been investigated for their potential role in supporting or treating Obsessive Compulsive Disorder (OCD), primarily due to their involvement in neurotransmitter synthesis. The most commonly studied amino acids in this context are L-tryptophan and L-tyrosine, which are precursors to serotonin and dopamine, respectively. Serotonin dysregulation is a well-established factor in OCD, and selective serotonin reuptake inhibitors (SSRIs) are a standard pharmacological treatment. Some small studies and case reports have explored whether supplementing with tryptophan (to increase serotonin production) might improve OCD symptoms. For example, a double-blind study from the 1990s found that tryptophan supplementation had a modest effect in reducing symptoms in adults with OCD, particularly when combined with SSRIs. Similarly, N-acetylcysteine (NAC), an amino acid derivative, has shown some promise in small trials for reducing OCD symptoms, possibly due to its influence on glutamate regulation. However, the evidence is limited and inconsistent, with most studies being small, uncontrolled, or showing only modest benefits. Major clinical guidelines do not recommend amino acid supplementation as a primary or standard treatment for OCD, but ongoing research continues to explore their adjunctive potential. Overall, while there is a biological rationale and some preliminary scientific support, the evidence base is not strong or conclusive, and amino acids should not replace established therapies.

More about amino acids
More about Obsessive Compulsive Disorder

Other ingredients used for Obsessive Compulsive Disorder

Other health conditions supported by amino acids

Products containing amino acids

Douglas Laboratories Free Form Amino