Glyceryl monolaurate (GML) is a monoglyceride known for its antimicrobial and anti-inflammatory properties. Its use in oral surgery is supported by a modest body of scientific evidence, primarily from in vitro studies and some preclinical research. GML has demonstrated the ability to disrupt biofilms and inhibit the growth of various oral pathogens, including Streptococcus mutans and Porphyromonas gingivalis, which are implicated in dental caries and periodontitis. These properties suggest a potential role in reducing postoperative infections and inflammation following oral surgical procedures.

Several studies have investigated GML's effects in the context of oral health. For example, in vitro experiments have shown that GML can reduce microbial colonization on oral surfaces and dental devices. Additionally, some formulations containing GML have been explored as adjuncts in mouthwashes or oral rinses to support wound healing and decrease microbial load post-surgery. However, robust clinical trials in humans specifically assessing its efficacy in oral surgery settings are limited. The available clinical data are insufficient to draw firm conclusions about its routine effectiveness as an adjunctive treatment after oral surgery.

Overall, while the scientific rationale for GML's use in supporting oral surgery is biologically plausible and supported by laboratory studies, the lack of high-quality human clinical trials means its use should be considered experimental or adjunctive pending further research.