Evidence supporting the use of: Lactobacillus reuteri
For the health condition: Oral Surgery

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus reuteri has been investigated for its potential benefits in oral health, particularly in the context of oral surgery and periodontal healing. There is a growing body of scientific literature supporting its adjunctive use alongside standard dental treatments. Several randomized controlled trials and systematic reviews suggest that L. reuteri probiotics can reduce postoperative inflammation, decrease pathogenic bacterial loads, and support tissue healing following procedures such as periodontal surgery, tooth extractions, and implant placement. The proposed mechanisms involve modulation of the local immune response, production of antimicrobial substances (such as reuterin), and restoration of healthy oral microbiota balance disrupted during surgery.

While the evidence is promising, particularly for reducing postoperative complications like alveolar osteitis (dry socket) and peri-implantitis, it is not yet definitive or universally accepted in clinical guidelines. The highest quality studies show moderate reductions in clinical markers of inflammation (such as bleeding on probing and pocket depth) when L. reuteri is used as an adjunct to scaling and root planing or post-surgical care. However, variation in probiotic strains, dosages, and study designs limits the ability to make strong, generalized recommendations. As such, while there is scientific validation for its supportive role in oral surgery, the evidence base can be considered moderate (rated 3/5), and further large-scale, standardized studies are warranted to clarify optimal usage protocols.

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