Evidence supporting the use of: Purified silver
For the health condition: Oral Surgery

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Purified silver, most commonly in the form of silver nanoparticles or silver ions, has been explored for use in oral surgery primarily due to its antimicrobial properties. Historically, silver compounds have been used for their ability to prevent and treat infections, and modern research has focused on leveraging these properties in dental and surgical contexts. In oral surgery, silver-containing dressings, gels, and coatings have been investigated for their potential to reduce postoperative infections, enhance wound healing, and prevent microbial colonization of implants or surgical sites. Several in vitro studies and animal models demonstrate that silver can inhibit a broad spectrum of oral pathogens, including those implicated in peri-implantitis and postoperative wound infections. However, clinical evidence supporting the routine use of purified silver in oral surgery is limited. While some small clinical trials and case reports suggest a benefit in reducing local infection rates, systematic reviews point out the paucity of high-quality evidence and the need for larger, well-designed randomized controlled trials. Concerns about cytotoxicity, delayed wound healing at higher concentrations, and the risk of developing silver resistance also temper enthusiasm for widespread use. Currently, silver is not a standard component in oral surgical protocols, but it may be considered in specific cases where infection risk is high, or in patients with compromised immunity, pending further research.

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