Evidence supporting the use of: Arctiin
For the health condition: Osteoporosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Arctiin is a lignan compound found primarily in the seeds of Arctium lappa (burdock). Recent preclinical studies have investigated the potential of arctiin in supporting bone health, particularly in the context of osteoporosis. Laboratory (in vitro) and animal (in vivo) research indicates that arctiin may promote osteoblast differentiation and inhibit osteoclast activity, processes that are crucial for bone formation and resorption, respectively. For example, a study published in Phytomedicine (2018) demonstrated that arctiin stimulated osteoblastic cells and suppressed osteoclastogenesis in mouse models, suggesting a possible preventative effect against bone loss. Another animal study found that arctiin administration mitigated bone loss in ovariectomized rats, a common model for postmenopausal osteoporosis. However, there are no robust clinical trials in humans evaluating arctiin’s efficacy or safety for osteoporosis treatment or prevention. Evidence is thus limited to laboratory and animal models, which may not fully translate to human outcomes. There is also no strong tradition of arctiin or burdock seed use specifically for osteoporosis in traditional medicine literature. In summary, while scientific interest is growing and preclinical evidence is promising, the overall level of evidence remains low, and arctiin should not be considered a validated therapy for osteoporosis pending further research.
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)Alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
lentinula edodes mycelia
lignans
maca
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
sardines
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
tomato
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
whey protein
zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
Equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
Animal Tissue
Antler
Apigenin
Algas calcareas
Acacetin
Astragaloside
Ampelopsin
Algal protein
Algalin
Abalone
Arctiin
Astragalin
Animal protein
Bok Choy
Bovine Protein
biochanin
Bone Protein
Calycosin
Cod Liver Oil
Cyanidin
Chinese Ligustrum berry
DHEA
Daidzein
Diosgenin
Drynaria
Diosmetin
epicatechin
Ecdysteroids
Eicosapentaenoic Acid
Eucommia ulmoides
Estrogen
Fo-Ti
formononetin
Fish
Flavanones
Flavans
Flavanols
Flavones
Hyperoside
Isoflavones
icariin
Kaempferol
Lycium
Lithothamnion
Legume protein
Mineral Blend
Marine Protein
Milk Protein
Naringenin
Neoeriocitrin
Puerarin
Phytoecdysteroid
Phaeophyceae
Polysaccharides
Procyanidin
Proanthocyanidins
Polyunsaturated Fat
Paeoniflorin
Phytoestrogens
Polymethoxylated flavones
Rehmannia
Soy
Soy Protein
silica
Shilajit
Stilbenoid
Ursolic Acid
Vegetable Protein
Wakame
Xanthophyll
Other health conditions supported by Arctiin
Cancer (natural therapy for)Cancer (prevention)
Diabetes
Free Radical Damage
Inflammation
Inflammatory Bowel Disorders
Osteoporosis
Rheumatoid Arthritis