Evidence supporting the use of: Blueberry
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Blueberry (Vaccinium spp.) has attracted interest in the context of osteoporosis due to its rich content of polyphenolic compounds, particularly anthocyanins and other antioxidants. Several preclinical studies have investigated the effects of blueberry supplementation on bone health, primarily in animal models. For example, research published in journals such as Journal of Bone and Mineral Research (2010) demonstrated that blueberry supplementation in ovariectomized rats—a commonly used model for postmenopausal osteoporosis—resulted in increased bone mass and improved bone structure. The proposed mechanisms include the modulation of oxidative stress and inflammation, both of which contribute to bone loss, as well as the upregulation of bone-forming pathways such as Wnt signaling.

Despite these promising findings in animals, direct evidence from human clinical trials is very limited. There are currently few, if any, well-designed, large-scale studies evaluating blueberry supplementation for the prevention or treatment of osteoporosis in humans. Most scientific validation remains at the preclinical stage, and the translation of these results to human populations is not yet established. Blueberries are not traditionally used in folk medicine specifically for osteoporosis, but their general health benefits and antioxidant properties have been widely recognized.

In summary, while there is some scientific basis (primarily from animal studies) suggesting blueberries may have a positive effect on bone health, the evidence in humans is insufficient, and thus, the overall support for their use in osteoporosis is modest.

More about blueberry
More about Osteoporosis

Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
Alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
Cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
Lentinula edodes mycelia
lignans
maca
magnesium
manganese
Microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
Whey protein
Zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
animal Tissue
antler
apigenin
Algas calcareas
Acacetin
astragaloside
ampelopsin
Algal protein
Algalin
Abalone
arctiin
astragalin
animal protein
bok choy
bovine protein
biochanin
bone protein
calycosin
cod liver oil
cyanidin
Chinese Ligustrum berry
DHEA
daidzein
diosgenin
Drynaria
diosmetin
epicatechin
ecdysteroids
eicosapentaenoic acid
Eucommia ulmoides
estrogen
fo-ti
formononetin
fish
flavanones
flavans
flavanols
flavones
Hyperoside
isoflavones
icariin
Kaempferol
Lycium
Lithothamnion
Legume protein
Mineral blend
Marine protein
Milk Protein
Naringenin
Neoeriocitrin
Puerarin
Phytoecdysteroid
Phaeophyceae
polysaccharides
procyanidin
proanthocyanidins
polyunsaturated fat
paeoniflorin
Phytoestrogens
polymethoxylated flavones
Rehmannia
Soy
Soy Protein
silica
Shilajit
Stilbenoid
Ursolic Acid
Vegetable Protein
Wakame
Xanthophyll

Products containing blueberry

Pure Encapsulations Açai 600
Pure Encapsulations CogniMag
Pure Encapsulations CurcumaSorb Mind
Designs For Health EssentiaGreens™
Douglas Laboratories Juvenon Pro Cognitive
Klean Athlete Klean Focus®
Klean Athlete Klean Multivitamin ™
Vitabase Life's Essentials Plus
Douglas Laboratories Liquid Multivitamin
Metagenics MetaKids Multi Soft Chew Grape
Douglas Laboratories Optimized Curcumin With Neurophenol™
Thorne Ovarian Care
Designs For Health PaleoGreens®
Designs For Health PaleoGreens®
Designs For Health PaleoReds®
Designs For Health PhytoBiome™
Metagenics PhytoGanix® Tropical Fruit
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Pure Encapsulations Poly-Prebiotic Powder
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations Polyphenol Nutrients
Designs For Health Primal Multi™
Pure Encapsulations PS Plus
Pure Encapsulations PureLean® Protein
Pure Encapsulations RevitalAge™ Ultra
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive ® 2 Daily
Douglas Laboratories Ultra Preventive ®-EZ Swallow
Douglas Laboratories Ultra Preventive® X
Douglas Laboratories Ultra Protein Green
Metagenics UltraMeal® Daily Support Dutch Chocolate
Metagenics UltraMeal Daily Support Mixed Berry
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs