Evidence supporting the use of: Blueberry
For the health condition: Osteoporosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Blueberry (Vaccinium spp.) has attracted interest in the context of osteoporosis due to its rich content of polyphenolic compounds, particularly anthocyanins and other antioxidants. Several preclinical studies have investigated the effects of blueberry supplementation on bone health, primarily in animal models. For example, research published in journals such as Journal of Bone and Mineral Research (2010) demonstrated that blueberry supplementation in ovariectomized rats—a commonly used model for postmenopausal osteoporosis—resulted in increased bone mass and improved bone structure. The proposed mechanisms include the modulation of oxidative stress and inflammation, both of which contribute to bone loss, as well as the upregulation of bone-forming pathways such as Wnt signaling.
Despite these promising findings in animals, direct evidence from human clinical trials is very limited. There are currently few, if any, well-designed, large-scale studies evaluating blueberry supplementation for the prevention or treatment of osteoporosis in humans. Most scientific validation remains at the preclinical stage, and the translation of these results to human populations is not yet established. Blueberries are not traditionally used in folk medicine specifically for osteoporosis, but their general health benefits and antioxidant properties have been widely recognized.
In summary, while there is some scientific basis (primarily from animal studies) suggesting blueberries may have a positive effect on bone health, the evidence in humans is insufficient, and thus, the overall support for their use in osteoporosis is modest.
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
lentinula edodes mycelia
lignans
maca
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
sardines
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
tomato
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
whey protein
zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
Equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
Animal Tissue
Antler
Apigenin
Algas calcareas
Acacetin
Astragaloside
Ampelopsin
Algal protein
Algalin
Abalone
Arctiin
Astragalin
Animal protein
Bok Choy
Bovine Protein
biochanin
Bone Protein
Calycosin
Cod Liver Oil
Cyanidin
Chinese Ligustrum berry
DHEA
Daidzein
Diosgenin
Drynaria
Diosmetin
epicatechin
Ecdysteroids
Eicosapentaenoic Acid
Eucommia ulmoides
Estrogen
Isoflavones
Milk Protein
Soy Protein
Other health conditions supported by blueberry
Alzheimer's DiseaseArteriosclerosis
Arthritis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cataracts
Chemotherapy (reducing side effects)
Cholera
Cholesterol (high)
Circulation (poor)
Circulation (to the brain)
Colds (antiviral)
Colds (general)
Colds (with fever)
Colitis
Colon (atonic)
Concentration (poor)
Confusion
Constipation (children)
Dementia
Diabetes
Diabetic Retinopathy
Diarrhea
Digestion (poor)
Eye Problems
Eyesight (poor)
Free Radical Damage
Hypertension
Inflammation
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Osteoporosis
Triglycerides (high)
Wrinkles
Products containing blueberry
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EssentiaGreens™
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Klean Athlete
Klean Focus®
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Klean Multivitamin ™
Vitabase
Life's Essentials Plus
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Liquid Multivitamin
Metagenics
MetaKids Multi Soft Chew Grape
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Optimized Curcumin With Neurophenol™
Thorne
Ovarian Care
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PaleoGreens®
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PaleoGreens®
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PaleoReds®
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PhytoBiome™
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PhytoGanix® Tropical Fruit
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PhytoMulti™ Multivitamin
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PhytoMulti With Iron
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PhytoMulti Without Iron
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PhytoMultivitamin
Pure Encapsulations
Poly-Prebiotic Powder
Pure Encapsulations
Polyphenol Nutrients
Pure Encapsulations
Polyphenol Nutrients
Designs For Health
Primal Multi™
Pure Encapsulations
PS Plus
Pure Encapsulations
PureLean® Protein
Pure Encapsulations
RevitalAge™ Ultra
Douglas Laboratories
Ultra Preventive
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Ultra Preventive
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Ultra Preventive ® 2 Daily
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Ultra Preventive ®-EZ Swallow
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Ultra Preventive® X
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Ultra Protein Green
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UltraMeal® Daily Support Dutch Chocolate
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UltraMeal Daily Support Mixed Berry
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Wellness Essentials Active Daily Packs
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Wellness Essentials Brain Health Daily Packs
Metagenics
Wellness Essentials® Daily Packs
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Wellness Essentials Healthy Balance Daily Packs
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Wellness Essentials Men's Vitality Daily Packs
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Wellness Essentials Women's Daily Packs
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Wellness Essentials Women's Prime Daily Packs