Evidence supporting the use of: Catechins
For the health condition: Osteoporosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Catechins, a group of polyphenolic compounds predominantly found in green tea, have been studied for their potential benefits in bone health and osteoporosis prevention. Preclinical studies, mainly in animal models and cell cultures, indicate that catechins can positively influence bone metabolism. Mechanistically, catechins act as antioxidants and anti-inflammatory agents, reducing oxidative stress that contributes to bone loss. Some studies suggest catechins may promote osteoblast (bone-forming cell) activity and inhibit osteoclast (bone-resorbing cell) differentiation, thus potentially increasing bone mineral density (BMD).
Human data, however, remain limited. A few observational studies have shown a correlation between higher green tea consumption and increased BMD or reduced fracture risk, particularly in postmenopausal women. For example, a study published in the "American Journal of Clinical Nutrition" (2017) associated habitual green tea consumption with a reduced risk of hip fracture. Nonetheless, these findings do not establish causality, and randomized controlled trials are sparse, with inconsistent results regarding catechin supplementation and direct improvement in osteoporosis outcomes.
In summary, while there is a plausible biological rationale and some preclinical and epidemiological evidence suggesting catechins may support bone health, robust clinical evidence is lacking. Current support for catechins in osteoporosis is preliminary, meriting a low to moderate evidence rating.
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)8-Prenylnaringenin
Abalone
Acacetin
Alfalfa
algal oil
Algal protein
Algalin
Algas calcareas
alpha-ketoglutarate (AKG)
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
animal Tissue
anthocyanins
antler
apigenin
arctiin
ashwagandha
astragalin
astragaloside
astragalus
barrenwort
beta caryophyllene
biochanin
blueberry
bok choy
bone protein
boron
bovine
bovine protein
broccoli
calcium
calycosin
catechins
caterpillar mushroom
Chinese Ligustrum berry
Cissus quadrangularis
cistanche
cod liver oil
collagen
collard
conjugated linoleic acid (CLA)
curcumin
cyanidin
daidzein
DHEA
DHEA (dehydroepiandrosterone)
dioscorea
diosgenin
diosmetin
DPA (docosapentaenoic acid)
Drynaria
ecdysteroids
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epicatechin
equol (proprietary)
estrogen
Eucommia ulmoides
fern
fish
fish protein
flavanols
flavanones
flavans
flavones
fo-ti
formononetin
genistein
genistin
glycitin
goji berry
gooseberry
haliotis
hesperetin
hesperidin
horsetail
Hyperoside
icariin
ipriflavone
isoflavones
Kaempferol
kale
knotweed
Legume protein
Lentinula edodes mycelia
lignans
Lithothamnion
Lycium
maca
magnesium
manganese
Marine protein
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk Protein
Mineral blend
Naringenin
Neoeriocitrin
olive
omega-3 fatty acids
paeoniflorin
Phaeophyceae
phosphorus
Phytoecdysteroid
Phytoestrogens
polymethoxylated flavones
polysaccharides
polyunsaturated fat
pomegranate
proanthocyanidins
procyanidin
prune
Puerarin
quercetin
red clover
Rehmannia
rehmannia glutinosa
resveratrol
royal jelly
rutin
seaweed
sesame
Shilajit
silica
silicon
Soy
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
Stilbenoid
strontium
tocotrienols
Ursolic Acid
Vegetable Protein
vitamin C
vitamin D
vitamin D3
vitamin K
Wakame
Whey protein
Xanthophyll
Zinc
Other health conditions supported by catechins
Alzheimer's DiseaseArteriosclerosis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Colds (antiviral)
Diabetes
Diarrhea
Digestion (poor)
Fatty Liver Disease
Free Radical Damage
Gastritis
Gingivitis
Hypertension
Inflammation
Influenza
Memory and Brain Function
Oral Surgery
Osteoporosis
Parkinson's Disease
Triglycerides (high)
