Evidence supporting the use of: Chinese Dodder
For the health condition: Osteoporosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Chinese Dodder (Cuscuta chinensis) has a long history of use in Traditional Chinese Medicine (TCM), where it is known as "Tu Si Zi." In TCM, Chinese Dodder seeds are traditionally prescribed to support kidney and liver function, which are both believed to be closely related to bone health and vitality. The herb is commonly included in herbal formulas aimed at addressing osteoporosis-like symptoms, especially in the elderly, based on the traditional view that “kidney deficiency” can lead to bone weakness.

There is limited modern scientific evidence supporting the use of Chinese Dodder specifically for osteoporosis. Some in vitro and animal studies suggest that extracts of Cuscuta chinensis may promote osteoblast (bone-forming cell) activity and inhibit osteoclast (bone-resorbing cell) differentiation, potentially favoring bone formation. For example, certain flavonoids and polysaccharides isolated from the seeds have shown bone-protective effects in ovariectomized rats, which are commonly used as a model for postmenopausal osteoporosis. However, these studies are preliminary, and robust clinical trials in humans are lacking.

Thus, the use of Chinese Dodder for osteoporosis is primarily justified by traditional practice, with only weak scientific support at this time. More research, particularly human studies, is needed to confirm efficacy and safety for this indication.

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