Evidence supporting the use of: Cistanche deserticola
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cistanche deserticola, a traditional Chinese medicinal herb, has been used historically to "tonify the kidney" and support bone health in Chinese medicine. In recent years, scientific studies—primarily in vitro and animal models—have investigated its potential role in the prevention and treatment of osteoporosis. Research suggests that extracts from Cistanche deserticola may have osteoprotective effects. For example, some studies have demonstrated that the phenylethanoid glycosides in Cistanche can promote osteoblast differentiation and inhibit osteoclast activity, leading to increased bone formation and reduced bone resorption in ovariectomized rats, a common model for postmenopausal osteoporosis. Additionally, the herb has shown antioxidant and anti-inflammatory properties, which may indirectly contribute to bone health. However, clinical trials in humans are lacking, and most evidence remains preclinical. As a result, while there is a scientific rationale for its use, and early findings are promising, the overall strength of evidence is modest, warranting further research before Cistanche deserticola can be confidently recommended for osteoporosis treatment or prevention in humans.

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