Evidence supporting the use of: Drynaria
For the health condition: Osteoporosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Drynaria, specifically Drynaria fortunei (commonly known as Gu Sui Bu), is a traditional Chinese medicinal herb that has historically been used for bone-related disorders, including fractures and osteoporosis. Its use is well-documented in Traditional Chinese Medicine (TCM) texts for promoting bone health and healing. In recent years, scientific interest has grown around Drynaria due to its potential effects on bone metabolism.
Preclinical studies have provided evidence supporting Drynaria's osteoprotective properties. Research in animal models of osteoporosis (such as ovariectomized rats) has demonstrated that extracts of Drynaria rhizome can increase bone mineral density, improve bone microarchitecture, and enhance markers of bone formation while reducing bone resorption. The active constituents, such as naringin and other flavonoids, are believed to stimulate osteoblast activity and suppress osteoclast differentiation, contributing to bone regeneration and maintenance.
However, while laboratory and animal studies are promising, high-quality human clinical trials are limited. Systematic reviews and meta-analyses suggest a potential benefit, but also highlight the need for more rigorous, large-scale clinical studies to confirm efficacy and safety in humans.
In summary, Drynaria is used both traditionally and has a moderate level of scientific evidence (primarily from preclinical and limited clinical data) to support its use for osteoporosis, but definitive clinical validation is still pending.
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)8-Prenylnaringenin
Abalone
Acacetin
Alfalfa
algal oil
Algal protein
Algalin
Algas calcareas
alpha-ketoglutarate (AKG)
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
animal Tissue
anthocyanins
antler
apigenin
arctiin
ashwagandha
astragalin
astragaloside
astragalus
barrenwort
beta caryophyllene
biochanin
blueberry
bok choy
bone protein
boron
bovine
bovine protein
broccoli
calcium
calycosin
catechins
caterpillar mushroom
Chinese Ligustrum berry
Cissus quadrangularis
cistanche
cod liver oil
collagen
collard
conjugated linoleic acid (CLA)
curcumin
cyanidin
daidzein
DHEA
DHEA (dehydroepiandrosterone)
dioscorea
diosgenin
diosmetin
DPA (docosapentaenoic acid)
Drynaria
ecdysteroids
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epicatechin
equol (proprietary)
estrogen
Eucommia ulmoides
fern
fish
fish protein
flavanols
flavanones
flavans
flavones
fo-ti
formononetin
genistein
genistin
glycitin
goji berry
gooseberry
haliotis
hesperetin
hesperidin
horsetail
Hyperoside
icariin
ipriflavone
isoflavones
Kaempferol
kale
knotweed
Legume protein
Lentinula edodes mycelia
lignans
Lithothamnion
Lycium
maca
magnesium
manganese
Marine protein
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk Protein
Mineral blend
Naringenin
Neoeriocitrin
olive
omega-3 fatty acids
paeoniflorin
Phaeophyceae
phosphorus
Phytoecdysteroid
Phytoestrogens
polymethoxylated flavones
polysaccharides
polyunsaturated fat
pomegranate
proanthocyanidins
procyanidin
prune
Puerarin
quercetin
red clover
Rehmannia
rehmannia glutinosa
resveratrol
royal jelly
rutin
seaweed
sesame
Shilajit
silica
silicon
Soy
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
Stilbenoid
strontium
tocotrienols
Ursolic Acid
Vegetable Protein
vitamin C
vitamin D
vitamin D3
vitamin K
Wakame
Whey protein
Xanthophyll
Zinc
Other health conditions supported by Drynaria
Broken BonesBruises (healing)
Cartilage Damage
Inflammation
Ligaments (torn or injured)
Osteoporosis
Sprains
Surgery (healing from)
Wounds and Sores
