Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Eucommia ulmoides, known as Du Zhong in traditional Chinese medicine (TCM), has a longstanding history of use for strengthening bones and promoting musculoskeletal health. In recent years, scientific studies have investigated its potential for supporting or treating osteoporosis. Laboratory and animal studies indicate that extracts from Eucommia ulmoides bark can promote osteoblast (bone-forming cell) proliferation and differentiation, while inhibiting osteoclast (bone-resorbing cell) activity. These effects are attributed to active compounds such as lignans, iridoids, and flavonoids, which appear to modulate pathways like the Wnt/β-catenin signaling and influence bone metabolism.

Several in vivo animal studies have reported that Eucommia ulmoides extract increases bone mineral density and improves bone microarchitecture in models of osteoporosis, such as ovariectomized rats. Some research also suggests anti-inflammatory and antioxidant effects that may contribute to bone protection. However, rigorous human clinical trials are lacking, and the current scientific evidence is primarily preclinical. While traditional use supports its application, modern validation is not yet robust. Thus, the evidence rating is moderate, with promising but not conclusive support for its use in osteoporosis.

More about Eucommia ulmoides
More about Osteoporosis

Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Abalone
Acacetin
Alfalfa
algal oil
Algal protein
Algalin
Algas calcareas
alpha-ketoglutarate (AKG)
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
animal Tissue
anthocyanins
antler
apigenin
arctiin
ashwagandha
astragalin
astragaloside
astragalus
barrenwort
beta caryophyllene
biochanin
blueberry
bok choy
bone protein
boron
bovine
bovine protein
broccoli
calcium
calycosin
catechins
caterpillar mushroom
Chinese Ligustrum berry
Cissus quadrangularis
cistanche
cod liver oil
collagen
collard
conjugated linoleic acid (CLA)
curcumin
cyanidin
daidzein
DHEA
DHEA (dehydroepiandrosterone)
dioscorea
diosgenin
diosmetin
DPA (docosapentaenoic acid)
Drynaria
ecdysteroids
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epicatechin
equol (proprietary)
estrogen
Eucommia ulmoides
fern
fish
fish protein
flavanols
flavanones
flavans
flavones
fo-ti
formononetin
genistein
genistin
glycitin
goji berry
gooseberry
haliotis
hesperetin
hesperidin
horsetail
Hyperoside
icariin
ipriflavone
isoflavones
Kaempferol
kale
knotweed
Legume protein
Lentinula edodes mycelia
lignans
Lithothamnion
Lycium
maca
magnesium
manganese
Marine protein
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk Protein
Mineral blend
Naringenin
Neoeriocitrin
olive
omega-3 fatty acids
paeoniflorin
Phaeophyceae
phosphorus
Phytoecdysteroid
Phytoestrogens
polymethoxylated flavones
polysaccharides
polyunsaturated fat
pomegranate
proanthocyanidins
procyanidin
prune
Puerarin
quercetin
red clover
Rehmannia
rehmannia glutinosa
resveratrol
royal jelly
rutin
seaweed
sesame
Shilajit
silica
silicon
Soy
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
Stilbenoid
strontium
tocotrienols
Ursolic Acid
Vegetable Protein
vitamin C
vitamin D
vitamin D3
vitamin K
Wakame
Whey protein
Xanthophyll
Zinc

Other health conditions supported by Eucommia ulmoides

Cardiovascular Disease
Cholesterol (high)
Diabetes
Fatty Liver Disease
Hypertension
Inflammation
Memory and Brain Function
Osteoporosis

Products containing Eucommia ulmoides

We currently have no products on Vitabase that contain this ingredient.