Evidence supporting the use of: Fish peptides (unspecified)
For the health condition: Osteoporosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Fish peptides are bioactive protein fragments derived from the enzymatic hydrolysis of fish proteins. There is emerging scientific interest in their potential role in supporting bone health, including in conditions like osteoporosis. Some in vitro and animal studies suggest that fish-derived peptides may promote osteoblast activity (cells responsible for bone formation) and inhibit osteoclast differentiation (cells responsible for bone resorption). The proposed mechanisms include enhancement of calcium absorption, antioxidant effects, modulation of inflammatory pathways, and upregulation of bone matrix proteins.
Human clinical evidence, however, remains limited. A small number of pilot studies and randomized controlled trials have investigated fish collagen peptides or fish protein hydrolysates in postmenopausal women and older adults. Some reported modest improvements in bone mineral density or markers of bone turnover. For example, a 2017 pilot study in postmenopausal women found that daily supplementation with fish collagen peptides resulted in increased bone mineral density at the spine after 6 months. However, these studies often have small sample sizes, short durations, and use different peptide preparations, making it difficult to draw firm conclusions.
In summary, while there is a plausible biological rationale and some early scientific evidence for the use of fish peptides in supporting bone health and potentially addressing osteoporosis, robust clinical evidence is currently lacking. Larger, long-term human studies are necessary to confirm their efficacy and safety for this indication.
More about Fish peptides (unspecified)
More about Osteoporosis
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)Alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
Cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
Lentinula edodes mycelia
lignans
maca
magnesium
manganese
Microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
Whey protein
Zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
animal Tissue
antler
apigenin
Algas calcareas
Acacetin
astragaloside
ampelopsin
Algal protein
Algalin
Abalone
arctiin
astragalin
animal protein
bok choy
bovine protein
biochanin
bone protein
calycosin
cod liver oil
cyanidin
Chinese Ligustrum berry
DHEA
daidzein
diosgenin
Drynaria
diosmetin
epicatechin
ecdysteroids
eicosapentaenoic acid
Eucommia ulmoides
estrogen
fo-ti
formononetin
fish
flavanones
flavans
flavanols
flavones
Hyperoside
isoflavones
icariin
Kaempferol
Lycium
Lithothamnion
Legume protein
Mineral blend
Marine protein
Milk Protein
Naringenin
Neoeriocitrin
Puerarin
Phytoecdysteroid
Phaeophyceae
polysaccharides
procyanidin
proanthocyanidins
polyunsaturated fat
paeoniflorin
Phytoestrogens
polymethoxylated flavones
Rehmannia
Soy
Soy Protein
silica
Shilajit
Stilbenoid
Ursolic Acid
Vegetable Protein
Wakame
Xanthophyll
Other health conditions supported by Fish peptides (unspecified)
ArthritisCholesterol (high)
Circulation (poor)
Diabetes
Hypertension
Inflammation
Osteoporosis
Triglycerides (high)
Wounds and Sores