Evidence supporting the use of: Hyperoside
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hyperoside is a flavonoid glycoside found in various medicinal plants, including Hypericum perforatum (St. John's Wort) and Crataegus species. There is emerging, though preliminary, scientific evidence suggesting that hyperoside may have beneficial effects on bone health and osteoporosis. Several in vitro and animal studies have reported that hyperoside can enhance osteoblast differentiation and function, promote bone formation, and inhibit osteoclast-mediated bone resorption. For example, a study published in Phytomedicine (2012) found that hyperoside could stimulate osteogenic differentiation of bone marrow stromal cells via the BMP and Wnt/β-catenin pathways. Other animal studies have shown that hyperoside supplementation can reduce bone loss in ovariectomized rats, a common model for postmenopausal osteoporosis, by modulating oxidative stress and inflammatory mediators.

However, there is a lack of robust clinical evidence in humans. To date, no large-scale randomized controlled trials have evaluated the efficacy or safety of hyperoside for osteoporosis in humans. Thus, while laboratory studies provide some scientific rationale and support a potential mechanism of action, the current level of evidence remains preclinical. Further clinical research is required to determine whether these effects translate to meaningful benefits in human osteoporosis prevention or treatment.

More about Hyperoside
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Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Abalone
Acacetin
Alfalfa
algal oil
Algal protein
Algalin
Algas calcareas
alpha-ketoglutarate (AKG)
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
animal Tissue
anthocyanins
antler
apigenin
arctiin
ashwagandha
astragalin
astragaloside
astragalus
barrenwort
beta caryophyllene
biochanin
blueberry
bok choy
bone protein
boron
bovine
bovine protein
broccoli
calcium
calycosin
catechins
caterpillar mushroom
Chinese Ligustrum berry
Cissus quadrangularis
cistanche
cod liver oil
collagen
collard
conjugated linoleic acid (CLA)
curcumin
cyanidin
daidzein
DHEA
DHEA (dehydroepiandrosterone)
dioscorea
diosgenin
diosmetin
DPA (docosapentaenoic acid)
Drynaria
ecdysteroids
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epicatechin
equol (proprietary)
estrogen
Eucommia ulmoides
fern
fish
fish protein
flavanols
flavanones
flavans
flavones
fo-ti
formononetin
genistein
genistin
glycitin
goji berry
gooseberry
haliotis
hesperetin
hesperidin
horsetail
Hyperoside
icariin
ipriflavone
isoflavones
Kaempferol
kale
knotweed
Legume protein
Lentinula edodes mycelia
lignans
Lithothamnion
Lycium
maca
magnesium
manganese
Marine protein
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk Protein
Mineral blend
Naringenin
Neoeriocitrin
olive
omega-3 fatty acids
paeoniflorin
Phaeophyceae
phosphorus
Phytoecdysteroid
Phytoestrogens
polymethoxylated flavones
polysaccharides
polyunsaturated fat
pomegranate
proanthocyanidins
procyanidin
prune
Puerarin
quercetin
red clover
Rehmannia
rehmannia glutinosa
resveratrol
royal jelly
rutin
seaweed
sesame
Shilajit
silica
silicon
Soy
soy isoflavones
Soy Protein
soybean
specialized pro-resolving mediators (SPMs)
Stilbenoid
strontium
tocotrienols
Ursolic Acid
Vegetable Protein
vitamin C
vitamin D
vitamin D3
vitamin K
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Xanthophyll
Zinc

Products containing Hyperoside

We currently have no products on Vitabase that contain this ingredient.