Evidence supporting the use of: Neoeriocitrin
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Neoeriocitrin and Osteoporosis: Evidence Synopsis

Neoeriocitrin is a flavonoid compound primarily found in citrus fruits, especially in the traditional Chinese medicinal plant Drynaria fortunei (Gu Sui Bu). Scientific interest in neoeriocitrin has increased due to its potential bone-protective properties.

Several preclinical studies have examined the effects of neoeriocitrin on osteoporosis models. In vitro, neoeriocitrin has been shown to promote osteoblast differentiation and inhibit osteoclast-mediated bone resorption, potentially via modulation of the Wnt/β-catenin and RANKL signaling pathways (Zhou et al., 2015). Animal studies suggest that supplementation with neoeriocitrin can prevent bone loss and improve bone microarchitecture in ovariectomized rats, a common model for postmenopausal osteoporosis (Wang et al., 2016).

Despite these promising findings, there is currently a lack of robust clinical trials in humans directly assessing the efficacy of neoeriocitrin for osteoporosis prevention or treatment. Most evidence remains preclinical, and the translation of these effects to humans is still uncertain. Therefore, while there is scientific rationale and preliminary data supporting its use, the overall evidence level is limited, justifying a rating of 2 out of 5.

More about Neoeriocitrin
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Other health conditions supported by Neoeriocitrin

Inflammation
Metabolic Syndrome
Osteoporosis

Products containing Neoeriocitrin

We currently have no products on Vitabase that contain this ingredient.