Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Neoeriocitrin and Osteoporosis: Evidence Synopsis

Neoeriocitrin is a flavonoid compound primarily found in citrus fruits, especially in the traditional Chinese medicinal plant Drynaria fortunei (Gu Sui Bu). Scientific interest in neoeriocitrin has increased due to its potential bone-protective properties.

Several preclinical studies have examined the effects of neoeriocitrin on osteoporosis models. In vitro, neoeriocitrin has been shown to promote osteoblast differentiation and inhibit osteoclast-mediated bone resorption, potentially via modulation of the Wnt/β-catenin and RANKL signaling pathways (Zhou et al., 2015). Animal studies suggest that supplementation with neoeriocitrin can prevent bone loss and improve bone microarchitecture in ovariectomized rats, a common model for postmenopausal osteoporosis (Wang et al., 2016).

Despite these promising findings, there is currently a lack of robust clinical trials in humans directly assessing the efficacy of neoeriocitrin for osteoporosis prevention or treatment. Most evidence remains preclinical, and the translation of these effects to humans is still uncertain. Therefore, while there is scientific rationale and preliminary data supporting its use, the overall evidence level is limited, justifying a rating of 2 out of 5.

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Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
Alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
lentinula edodes mycelia
lignans
maca
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
sardines
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
tomato
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
whey protein
zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
Equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
Animal Tissue
Antler
Apigenin
Algas calcareas
Acacetin
Astragaloside
Ampelopsin
Algal protein
Algalin
Abalone
Arctiin
Astragalin
Animal protein
Bok Choy
Bovine Protein
biochanin
Bone Protein
Calycosin
Cod Liver Oil
Cyanidin
Chinese Ligustrum berry
DHEA
Daidzein
Diosgenin
Drynaria
Diosmetin
epicatechin
Ecdysteroids
Eicosapentaenoic Acid
Eucommia ulmoides
Estrogen
Fo-Ti
formononetin
Fish
Flavanones
Flavans
Flavanols
Flavones
Hyperoside
Isoflavones
icariin
Kaempferol
Lycium
Lithothamnion
Legume protein
Mineral Blend
Marine Protein
Milk Protein
Naringenin
Neoeriocitrin
Puerarin
Phytoecdysteroid
Phaeophyceae
Polysaccharides
Procyanidin
Proanthocyanidins
Polyunsaturated Fat
Paeoniflorin
Phytoestrogens
Polymethoxylated flavones
Rehmannia
Soy
Soy Protein
silica
Shilajit
Stilbenoid
Ursolic Acid
Vegetable Protein
Wakame
Xanthophyll

Other health conditions supported by Neoeriocitrin

Inflammation
Metabolic Syndrome
Osteoporosis

Products containing Neoeriocitrin

We currently have no products on Vitabase that contain this ingredient.