Evidence supporting the use of: Silica
For the health condition: Osteoporosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Silica (silicon dioxide) has been investigated for its potential role in bone health, including the prevention and management of osteoporosis. Scientific interest arises from the observation that silicon is present in bone tissue and may play a role in bone formation and mineralization processes. Several animal studies and limited human observational studies have suggested that dietary silicon intake is positively associated with bone mineral density (BMD), particularly in premenopausal women. Some mechanisms proposed include silica’s involvement in collagen synthesis and the stimulation of osteoblast (bone-forming cell) activity.
However, direct evidence supporting the use of supplemental silica for the treatment or prevention of osteoporosis in humans is limited. Most clinical studies are observational, with few randomized controlled trials. The available interventional studies are small in sample size and sometimes use forms of silicon different from over-the-counter silica supplements. As a result, reputable organizations, including the National Osteoporosis Foundation, do not currently recommend silica supplementation as a primary or adjunct therapy for osteoporosis.
In summary, while there is a scientific rationale for investigating silica’s effects on bone health, robust clinical evidence is lacking. The current evidence base is insufficient to strongly support the use of silica supplements for osteoporosis, and its efficacy remains unproven in large, well-designed human trials.
Other ingredients used for Osteoporosis
7-hydroxymatairesinol (HMR)alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
lentinula edodes mycelia
lignans
maca
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
sardines
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
tomato
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
whey protein
zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
Equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
Animal Tissue
Antler
Apigenin
Algas calcareas
Acacetin
Astragaloside
Ampelopsin
Algal protein
Algalin
Abalone
Arctiin
Astragalin
Animal protein
Bok Choy
Bovine Protein
biochanin
Bone Protein
Calycosin
Cod Liver Oil
Cyanidin
Chinese Ligustrum berry
DHEA
Daidzein
Diosgenin
Drynaria
Diosmetin
epicatechin
Ecdysteroids
Eicosapentaenoic Acid
Eucommia ulmoides
Estrogen
Isoflavones
Milk Protein
Soy Protein
Other health conditions supported by silica
Broken BonesHair (loss or thinning)
Osteoporosis
Skin Care (general)
Wrinkles