Evidence supporting the use of: Vitamin D (cholecalciferol)
For the health condition: Osteoporosis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin D (cholecalciferol) is widely used in the support and treatment of osteoporosis, and this use is solidly based on scientific evidence. Vitamin D plays a critical role in calcium homeostasis and bone metabolism by enhancing the intestinal absorption of calcium and phosphate—minerals essential for bone mineralization. Deficiency in vitamin D can lead to decreased calcium absorption, secondary hyperparathyroidism, bone loss, and increased fracture risk. Large-scale randomized controlled trials and meta-analyses have shown that vitamin D supplementation, particularly when combined with calcium, can reduce bone loss and lower the risk of fractures in older adults—especially those who are deficient in vitamin D or at high risk for osteoporosis. Guidelines from major health organizations, such as the National Osteoporosis Foundation and the Endocrine Society, recommend vitamin D supplementation as part of osteoporosis management and prevention strategies. However, while vitamin D alone may not be sufficient to significantly reduce fracture risk, it is considered essential as an adjunct to other osteoporosis therapies. Excessive supplementation is not advised, as very high doses may carry risks. Overall, the use of cholecalciferol for osteoporosis is well-validated by current scientific evidence.

More about Vitamin D (cholecalciferol)
More about Osteoporosis

Products containing Vitamin D (cholecalciferol)

We currently have no products on Vitabase that contain this ingredient.