Evidence supporting the use of: Vitamin K (Phylloquinone)
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin K (Phylloquinone) and Osteoporosis: There is some scientific interest in the possible role of vitamin K in bone health, including osteoporosis. Vitamin K is essential for the γ-carboxylation of osteocalcin, a protein involved in bone mineralization. Some observational studies have shown that low vitamin K intake is associated with lower bone mineral density and increased fracture risk. Furthermore, randomized controlled trials (RCTs), especially with vitamin K2 (menaquinone), have shown modest benefits in reducing bone loss and fracture risk, particularly in Japanese populations. However, the evidence for phylloquinone (vitamin K1), the main dietary form, is less robust. Meta-analyses of RCTs have found limited or inconsistent benefits for vitamin K1 supplementation in improving bone mineral density or reducing fractures in postmenopausal women and older adults. Guidelines from major osteoporosis organizations do not recommend vitamin K supplementation specifically for osteoporosis prevention or treatment due to insufficient high-quality evidence. Overall, while vitamin K has a biological role in bone health and some early studies were promising, the current scientific consensus is that the evidence for using vitamin K1 (phylloquinone) as a standalone treatment for osteoporosis is limited and not conclusive.

More about Vitamin K (Phylloquinone)
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Other health conditions supported by Vitamin K (Phylloquinone)

Bleeding (external)
Bleeding (internal)
Blood Clots (prevention of)
Osteoporosis

Products containing Vitamin K (Phylloquinone)

We currently have no products on Vitabase that contain this ingredient.