Evidence supporting the use of: Estrogen
For the body system: Ovaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Estrogen is a well-established hormone with a scientifically validated role in supporting the ovaries and the broader female reproductive system. Estrogen is produced primarily by the ovaries and is essential for the regulation of the menstrual cycle, development of secondary sexual characteristics, and maintenance of reproductive tissues. Scientific evidence strongly supports the use of estrogen in clinical settings such as hormone replacement therapy (HRT) for menopausal symptoms, where endogenous estrogen production declines. Numerous randomized controlled trials and decades of clinical practice have demonstrated that estrogen therapy alleviates hot flashes, prevents bone loss, and supports urogenital health in postmenopausal women. Additionally, estrogen is used in assisted reproductive technologies to help prepare the endometrium for implantation. The mechanism of action is well-understood: estrogen binds to estrogen receptors in target tissues, modulating gene expression and cellular function. The use of estrogen for ovarian and reproductive system support is not based on tradition alone but is grounded in robust scientific research, clinical guidelines, and regulatory approvals. However, estrogen therapy is carefully managed due to potential risks, including thromboembolism and certain cancers, highlighting the importance of individualized medical supervision.

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Products containing estrogen

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