Evidence supporting the use of: Formononetin
For the body system: Ovaries

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Formononetin is a naturally occurring isoflavone found in plants such as red clover (Trifolium pratense). Its use in supporting the ovaries and female reproductive health is primarily rooted in traditional herbal practices rather than modern scientific validation. Historically, red clover has been used in traditional medicine to address symptoms associated with menopause and menstruation, likely due to its phytoestrogen content, including formononetin. Phytoestrogens are plant-derived compounds that can weakly mimic the effects of estrogen in the body, potentially influencing hormonal balance.

While there are some in vitro and animal studies suggesting that formononetin and related isoflavones can bind to estrogen receptors and exhibit estrogen-like effects, robust clinical trials in humans specifically linking formononetin to direct ovarian support or improved ovarian function are lacking. Most available research focuses on broader outcomes such as menopausal symptom relief or general hormonal modulation. Therefore, the evidence for the effectiveness of formononetin in supporting the ovaries is predominantly based on traditional use and extrapolation from studies on isoflavones as a group, rather than on direct scientific evidence for this specific ingredient and body system.

More about formononetin
More about Ovaries

Other body systems supported by formononetin

Estrogen
Female Reproductive System
Heart
Ovaries
Reproductive System

Products containing formononetin

We currently have no products on Vitabase that contain this ingredient.